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Identification of novel imprinted differentially methylated regions by global analysis of human parthenogenetic induced pluripotent stem cells

(Submitter supplied) Parental imprinting is an epigenetic phenomenon by which genes are expressed in a monoallelic fashion, according to their parent-of-origin. DNA methylation is considered the hallmark mechanism regulating parental imprinting. To identify imprinted differentially methylated regions (DMRs), we compared the DNA methylation status between multiple normal and parthenogenetic human pluripotent stem cells (PSCs) by performing reduced representation bisulfite sequencing. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL11154
8 Samples
Download data: BED
Series
Accession:
GSE47088
ID:
200047088

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