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Expression data from transplanted HCmel3 mouse melanomas relapsing to adoptive T-cell therapy in vivo

(Submitter supplied) Adoptive cell therapies (ACT) with cytotoxic T-cell targeting melanocytic antigens can achieve remissions in metastatic melanoma patients, but tumours frequently relapse. To study the underlying mechanisms of resistance we have generated a genetically engineered mouse melanoma model that faithfully recapitulates tumour regression, remission and relapse as seen in patients. HCmel3 mouse melanoma cells were injected into syngneic C57/BL6 (H-2b) mice. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL6887
21 Samples
Download data:
GEO (TXT)
Series
Accession:
GSE40213
ID:
200040213

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