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    Dynamics of enhancer chromatin signatures mark the transition from pluripotency to cell specification during embryogenesis

    (Submitter supplied) The generation of distinctive cell types that form different tissues and organs requires precise, temporal and spatial control of gene expression. This depends on specific cis-regulatory elements distributed in the non-coding DNA surrounding their target genes. Studies performed on mammalian embryonic stem cells and Drosophila embryos suggest that active enhancers form part of a defined chromatin landscape marked by histone H3 lysine 4 mono-methylation (H3K4me1) and histone H3 lysine 27 acetylation (H3K27ac). more...
    Organism:
    Danio rerio
    Type:
    Genome binding/occupancy profiling by high throughput sequencing
    Platform:
    GPL10164
    24 Samples
    Download data:
    GEO (BED, WIG), SRA SRP008826
    Series
    Accession:
    GSE32483
    ID:
    200032483

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