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    Gene Expression profiling in DBA/2J glaucoma

    (Submitter supplied) Glaucoma is a common ocular disorder that is a leading cause of blindness worldwide. It is characterized by the dysfunction and loss of retinal ganglion cells (RGCs). Although many studies have implicated various molecules in glaucoma, no mechanism has been shown to be responsible for the earliest detectable damage to RGCs and their axons in the optic nerve. Here, we show that the leukocyte transendothelial migration pathway is activated in the optic nerve head at the earliest stages of disease in an inherited mouse model of glaucoma. more...
    Organism:
    Mus musculus
    Type:
    Expression profiling by array; Third-party reanalysis
    Platform:
    GPL1261
    49 Samples
    Download data:
    GEO (CEL, TXT)
    Series
    Accession:
    GSE36833
    ID:
    200036833

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