Format
Sort by

Send to:

Choose Destination

Links from PubMed

Items: 2

1.

PPARg agonists induce a white-to-brown fat conversion through stabilization of PRDM16 protein

(Submitter supplied) Brown adipose tissue dissipates energy through heat and functions as a defense against cold and obesity. PPARγ ligands have been shown to induce the browning of white adipocytes; however, the underlying mechanisms remain unclear. Here we show that PPARγ ligands require full agonism to induce a brown fat gene program preferentially in subcutaneous white adipose. These effects require expression of PRDM16, a factor that controls the development of classical brown fat. more...
Organism:
Mus musculus
Type:
Expression profiling by array
Dataset:
GDS4021
Platform:
GPL8321
8 Samples
Download data:
GEO (CEL)
Series
Accession:
GSE35011
ID:
200035011
2.
Full record GDS4021

Rosiglitazone effect on PRDM16-deficient inguinal white adipose tissue: stromal-vascular cells

Analysis of SV cells isolated from PRDM16-depleted inguinal white adipose tissue (WAT) treated with rosiglitazone. Antidiabetic PPARγ ligand drugs, such as rosiglitazone, activate a browning of WAT. Results provide insight into molecular mechanisms underlying white-to-brown fat conversion.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 agent, 2 genotype/variation sets
Platform:
GPL8321
Series:
GSE35011
8 Samples
Download data:
GEO (CEL)

Supplemental Content

Find related data

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Write to the Help Desk