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Items: 4

1.

Custom Illumina array DNA methylation analysis of 384 CpGs across five cancer types

(Submitter supplied) Tumor heterogeneity is a major barrier to effective cancer diagnosis and treatment. We recently identified cancer-specific differentially DNA-methylated regions (cDMRs) in colon cancer, which also distinguish normal tissue types from each other. We therefore hypothesized that these colon cDMRs might also be cDMRs for other cancer types. For colon, lung, breast, thyroid, and Wilms tumors, we show stochastic variation in methylation within each tumor type, but involving the same loci across tumor types, with intermediate values of variation for premalignant adenomas.
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL13645
290 Samples
Download data:
GEO (TXT)
Series
Accession:
GSE29505
ID:
200029505
2.

Chip-chip from Human Pulmonary Fibroblasts with H3K9me2 antibody

(Submitter supplied) Histone modification H3K9me2 is associated heterochromatin and gene silencing, but the relationship between DNA methylation and H9K9me2 haven’t been checked in a genome-wide scale. This dataset was generated to compare with genome-wide DNA methylation data.
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by genome tiling array
4 related Platforms
4 Samples
Download data:
GEO (TXT, XYS)
Series
Accession:
GSE29381
ID:
200029381
3.

DNA copy number variation from human Wilms' Tumor samples

(Submitter supplied) Genome-wide DNA copy number was studied to determine whether the Wilms' tumor samples generally show normal copy number variation comparing to the colon tumor samples We used custom Nimblegen microarrays to determine the genome-wide DNA copy number in human Wilms' Tumor samples
Organism:
Homo sapiens
Type:
Genome variation profiling by genome tiling array
Platform:
GPL13611
5 Samples
Download data:
GEO (XYS)
Series
Accession:
GSE29374
ID:
200029374
4.

DNA methylation data from human liver, frontal cortex, spleen and colon

(Submitter supplied) DNA methylation data from human tissues: 5 samples each of normal liver, frontal cortex, spleen and colon. 5 samples of colon tumor.
Organism:
Homo sapiens
Type:
Methylation profiling by genome tiling array
Platform:
GPL9275
25 Samples
Download data:
GEO (TXT, XYS)
Series
Accession:
GSE23841
ID:
200023841
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