GEO DataSet Links for PubMed (Select 21357277) - GEO DataSets

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Items: 2

Select item 2000236431.

Cardiac transcriptome profiles of S.LEW congenic strain compared with the hypertensive Dahl S rat

(Submitter supplied) Despite inheritance of hypertension in families, identifying genetic mechanisms predisposing individuals to hypertension has remained challenging. The effects of single genes contributing to the development of hypertension may not be readily detected in individuals whose genomes also contain other genetic factors that resist hypertension. By using a highly permissive rat genome for inherited hypertension, we demonstrate that increased expression of one such gene, Rififylin (Rffl), is a novel inherited risk factor for hypertension and increased mortality. more...

Organism:: Rattus norvegicus

Type:: Expression profiling by array

Dataset:: GDS3873
Platform:: GPL1355
6 Samples

Download data: CEL, CHP

Series

Accession:: GSE23643

ID:: 200023643

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Select item 38732.

Hypertension: heart

Analysis of heart from low-salt diet fed, 53-day old males representing hypertensive, salt-sensitive (S) Dahl strain and congenic strain S.LEW(10)x12x2x3x5. Results provide further insight into molecular basis of hypertension development.