Display Settings:

Format

Send to:

Choose Destination
We are sorry, but NCBI web applications do not support your browser and may not function properly. More information

    Mammalian Dpy-30 regulates genomic H3K4 methylation and is essential for ES cell fate specification

    (Submitter supplied) H3K4 methylation is associated with active genes and, along with H3K27 methylation, is part of a bivalent chromatin mark that typifies poised developmental genes in ESCs. However, its functional roles in ESC maintenance and differentiation are not established. Here we show that mammalian Dpy-30, a core subunit of SET1/MLL complexes, biochemically modulates H3K4 methylation in vitro, and directly regulates chromosomal H3K4me3 throughout the mammalian genome. more...
    Organism:
    Mus musculus
    Type:
    Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
    Platforms:
    GPL11002 GPL9250 GPL6885
    10 Samples
    Download data:
    GEO (BED, TXT, WIG), SRA SRP006206
    Series
    Accession:
    GSE26136
    ID:
    200026136

      Supplemental Content

      Recent activity

      Your browsing activity is empty.

      Activity recording is turned off.

      Turn recording back on

      See more...
      Write to the Help Desk