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    Conservation and divergence of methylation patterning in plants and animals

    (Submitter supplied) Cytosine DNA methylation is a heritable epigenetic mark present in many eukaryotic organisms. While DNA methylation likely has a conserved role in gene silencing, the levels and patterns of DNA methylation appear to vary drastically among different organisms. Here, we used shotgun genomic bisulfite sequencing (BS-Seq) to compare DNA methylation in eight diverse plant and animal genomes. We found that patterns of methylation are very similar in flowering plants with methylated cytosines detected in all sequence contexts, whereas CG methylation predominates in animals. more...
    Oryza sativa; Danio rerio; Arabidopsis thaliana; Ciona intestinalis; Mus musculus; Populus trichocarpa; Apis mellifera; Chlamydomonas reinhardtii
    Methylation profiling by high throughput sequencing
    9 related Platforms
    14 Samples
    Download data:
    GEO (TXT), SRA SRP002239

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