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    ChIP-seq Accurately Predicts Tissue-Specific Activity of Enhancers

    (Submitter supplied) Determining the spatial and temporal activity patterns of enhancers remains a challenge in the functional annotation of the human genome. Here, we performed genome-wide mapping of tissue-specific in vivo binding sites for the enhancer-associated protein p300 and assessed in transgenic mice the utility of this information in identifying enhancers and predicting their activity patterns. Chromatin immunoprecipitation followed by massively-parallel sequencing was used to identify p300-enriched sites in mouse embryonic day 11.5 (e11.5) forebrain, midbrain, and limb. more...
    Organism:
    Mus musculus
    Type:
    Genome binding/occupancy profiling by high throughput sequencing
    Platform:
    GPL9185
    3 Samples
    Download data:
    GEO (TXT), SRA SRP000600
    Series
    Accession:
    GSE13845
    ID:
    200013845

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