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    NOD2 and human ileal gene expression

    (Submitter supplied) Profiling of ileal mucosal gene expression in Chron's disease patients with and without NOD2 risk alleles; through microarray analyses it was discovered that 18 genes related to lymphocyte and phagocyte activation recuitment were upregulated in affected ileum in NOD2R patients as compared to ileum in NOD2s (no risk alleles) patients, thus supporting the concept that NOD2 risk alleles contribute to impaired regulation of inflammation in the ileum.
    Organism:
    Homo sapiens
    Type:
    Expression profiling by array
    Platforms:
    GPL4133 GPL6848
    20 Samples
    Download data:
    GEO (GPR)
    Series
    Accession:
    GSE17594
    ID:
    200017594

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