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    Results: 2

    1.

    Hi-C Expression Data

    (Submitter supplied) We describe Hi-C, a method that probes the three-dimensional architecture of whole genomes by coupling proximity-based ligation with massively parallel sequencing. We constructed spatial proximity maps of the human genome with Hi-C at a resolution of 1Mb. These maps confirm the presence of chromosome territories and the spatial proximity of small, gene-rich chromosomes. We identified an additional level of genome organization that is characterized by the spatial segregation of open and closed chromatin to form two genome-wide compartments. more...
    Organism:
    Homo sapiens
    Type:
    Expression profiling by array
    Platform:
    GPL570
    2 Samples
    Download data:
    GEO (CEL)
    Series
    Accession:
    GSE18350
    ID:
    200018350
    2.

    Comprehensive mapping of long-range interactions reveals folding principles of the human genome.

    (Submitter supplied) We describe Hi-C, a method that probes the three-dimensional architecture of whole genomes by coupling proximity-based ligation with massively parallel sequencing. We constructed spatial proximity maps of the human genome with Hi-C at a resolution of 1Mb. These maps confirm the presence of chromosome territories and the spatial proximity of small, gene-rich chromosomes. We identified an additional level of genome organization that is characterized by the spatial segregation of open and closed chromatin to form two genome-wide compartments. more...
    Organism:
    Homo sapiens
    Type:
    Genome binding/occupancy profiling by high throughput sequencing; Other
    Platform:
    GPL9052
    8 Samples
    Download data:
    GEO (TXT, ZIP), SRA SRP001261
    Series
    Accession:
    GSE18199
    ID:
    200018199

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