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Transcriptional Signature and Memory Retention of Human-induced Pluripotent Stem Cells

(Submitter supplied) Transient expression of two factors, or from Oct4 alone, resulted in efficient generation of human iPSCs. The reprogramming strategy described revealed a potential transcriptional signature for human iPSCs yet retaining the gene expression of donor cells in human reprogrammed cells free of viral and transgene interference. Genetic reprogramming of somatic cells to a pluripotent state (induced pluripotent stem cells or iPSCs) by over-expression of specific genes has been accomplished using mouse and human cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
15 Samples
Download data:
GEO (CEL)
Series
Accession:
GSE18618
ID:
200018618

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