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    Distinct transcriptional outputs associated with mono- and di-methylated histone H3 arginine 2

    (Submitter supplied) Dimethylation of histone H3 arginine 2 (H3R2me2) maintains transcriptional silencing by inhibiting Set-1 mediated trimethylation of H3K4. Here we demonstrate that arginine 2 is also monomethylated (H3R2me1) in yeast but that its functional characteristics are distinct from H3R2me2: (a) H3R2me1 does not inhibit H3K4 methylation, (b) it is present throughout the coding region of genes and (c) it correlates with active transcription. more...
    Organism:
    Saccharomyces cerevisiae
    Type:
    Genome binding/occupancy profiling by genome tiling array
    Platform:
    GPL5683
    6 Samples
    Download data:
    GEO (PAIR, TXT)
    Series
    Accession:
    GSE14453
    ID:
    200014453

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