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    Results: 2

    1.

    Tumor Liver vs Normal Liver: ChIP-chip and RNA expression

    (Submitter supplied) There is widespread interest in efficient characterization of differences between tumor and normal samples. Here, we demonstrate an effective methodology for genome-scale characterization of tumors. Using matched normal and tumor samples from liver cancer patients, as well as non-cancer-related normal liver tissue, we first determined changes in gene expression as monitored on RNA expression arrays. more...
    Organism:
    Homo sapiens
    Type:
    Expression profiling by genome tiling array
    4 related Platforms
    45 Samples
    Download data:
    GEO (CSV, IDAT, LOCS, TIFF, TXT, XML)
    Series
    Accession:
    GSE10842
    ID:
    200010842
    2.

    Using ChIP-chip technology to reveal common principles of transcriptional repression in normal and cancer cells

    (Submitter supplied) We compared 12 different cell populations, including embryonic stem cells before and during differentiation into embryoid bodies as well as various types of normal and tumor cells to determine if pluripotent vs. differentiated cell types use different mechanisms to establish their transcriptome. We first identified genes that were not expressed in the 12 different cell populations and then determined which of them were regulated by histone methylation, DNA methylation, at the step of productive elongation, or by the inability to establish a pre-initiation complex. more...
    Organism:
    Mus musculus; Homo sapiens
    Type:
    Expression profiling by genome tiling array; Methylation profiling by array
    9 related Platforms
    47 Samples
    Download data:
    GEO (CSV, IDAT, JPG, PAIR, TIFF, TXT, XML)
    Series
    Accession:
    GSE10504
    ID:
    200010504

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