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Changes in transcription patterns in BoMac cells in response to PDD spirochetes

(Submitter supplied) Papillomatous digital dermatitis (PDD) is a polymicrobial infection in soft tissue adjacent to the hoof and is the leading cause of lameness in dairy cattle. Treponema phagedenis-like (TPL) spirochetes are a constant feature of PDD lesions and are localized deep in infected tissue. Host-cell response mechanisms to TPL bacteria are poorly understood. To assess how bovine macrophages respond to cellular constituents of TPL spirochetes, changes in transcription were analyzed using serial analysis of gene expression (SAGE) and real time RT-PCR. more...
Organism:
Bos taurus
Type:
Expression profiling by SAGE
Platform:
GPL223
2 Samples
Download data:
GEO
Series
Accession:
GSE6702
ID:
200006702

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