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Items: 2

1.

Characterization of weight loss and weight regain mechanisms after Roux-en-Y gastric bypass in rats

(Submitter supplied) Roux-en-Y gastric bypass (RYGB) is the most effective therapy for morbid obesity, but it has a ~20% failure rate. We used our established RYGB model in diet-induced obese (DIO) Sprague-Dawley rats, which reproduces human bi-phasic body weight (BW) loss pattern, to determine mechanisms contributing to success (RGYB-S) or failed (RYGB-F) RYGB. DIO rats were randomized to RYGB, sham operated Obese, and sham operated obese pair fed-linked to RYGB (PF) groups. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Dataset:
GDS2956
Platform:
GPL1355
18 Samples
Download data:
GEO (CEL, CHP)
Series
Accession:
GSE8314
ID:
200008314
2.
Full record GDS2956

Roux-en-Y gastric bypass model

Analysis of subcutaneous abdominal fat and hypothalami of male Sprague-Dawleys that lost or regained weight after Roux-en-Y gastric bypass (RYGB) surgery. Obesity induced by diet prior to RYBG. Results provide insight into the mechanisms contributing to successful weight loss following RYBG.
Organism:
Rattus norvegicus
Type:
Expression profiling by array, count, 3 disease state, 3 other, 2 protocol, 2 tissue sets
Platform:
GPL1355
Series:
GSE8314
18 Samples
Download data:
GEO (CEL, CHP)
DataSet
Accession:
GDS2956
ID:
2956

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