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    Transcript Specificity in Yeast Pre-mRNA Splicing Revealed by Mutations in Core Spliceosomal Components

    (Submitter supplied) Appropriate expression of most eukaryotic genes requires the removal of introns from their pre-messenger RNAs (pre-mRNAs), a process catalyzed by the spliceosome. In higher eukaryotes a large family of auxiliary factors known as SR proteins can improve the splicing efficiency of transcripts containing suboptimal splice sites by interacting with distinct sequences present in those pre-mRNAs. The yeast Saccharomyces cerevisiae lacks functional equivalents of most of these factors; thus, it has been unclear whether the spliceosome could effectively distinguish among transcripts. more...
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array
    Platform:
    GPL5052
    297 Samples
    Download data:
    GEO (GPR)
    Series
    Accession:
    GSE7419
    ID:
    200007419

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