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    Results: 2

    1.

    Expression data from wild type versus HDAC knock out mouse embryonic stem cells

    (Submitter supplied) Histone deacetylase 1 (HDAC1) is an enzyme that promotes deacetylation of acetylated lysine residues in histones and other proteins. Histone acetylation is often associated with gene activation and expression. Los of HDAC1 leads to severe problems in development and proliferation. Moreover, it seems to be the major histone deacetylase in mouse embryonic stem cells. We used microarrays to identify putative HDAC1 target genes. more...
    Organism:
    Mus musculus
    Type:
    Expression profiling by array
    Dataset:
    GDS2294
    Platform:
    GPL81
    6 Samples
    Download data:
    GEO (CAB, CEL, EXP, XLS)
    Series
    Accession:
    GSE5583
    ID:
    200005583
    2.
    Full record GDS2294

    Histone deacetylase 1 deficient embryonic stem cells

    Analysis of embryonic stem cells lacking histone deacetylase 1 (HDAC1). HDACs catalyze the removal of acetyl groups from core histones resulting in chromatin compaction. Results provide insight into the role of HDAC1 in transcriptional regulation.
    Organism:
    Mus musculus
    Type:
    Expression profiling by array, count, 2 genotype/variation sets
    Platform:
    GPL81
    Series:
    GSE5583
    6 Samples
    Download data:
    GEO (CEL, EXP)

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