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Full record GDS4508

Histone methyltransferase ESET knockout effect on embryonic dorsal telencephalon

Analysis of dorsal telencephalon from E14.5 embryos depleted of histone methyltransferase ESET. ESET ablation leads to decreased H3K9 trimethylation and misregulation of genes resulting in severe brain defects and embryonic lethality. Results provide insight into role of ESET in brain development.
Organism:
Mus musculus
Type:
Expression profiling by array, count, 2 genotype/variation sets
Platform:
GPL1261
Series:
GSE40296
6 Samples
Download data: CEL
DataSet
Accession:
GDS4508
ID:
4508

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