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    Results: 6

    1.
    Full record GDS3677

    High-fat-diet model: liver

    Analysis of liver from obesity-prone (OP) Wistar males with nonalcoholic fatty liver disease (NAFLD) induced by a 16 week, high-fat diet (HFD). Obesity-resistant (OR) males, fed an identical diet, were also examined. Results provide insight into molecular mechanisms underlying NAFLD pathogenesis.
    Organism:
    Rattus norvegicus
    Type:
    Expression profiling by array, log ratio, 2 disease state sets
    Platform:
    GPL4294
    Series:
    GSE11492
    8 Samples
    Download data:
    GEO (TXT)
    DataSet
    Accession:
    GDS3677
    ID:
    3677
    2.

    Transcript Profiling of High Fat Diet induced Obesity-prone and Obesity-resistant Rats

    (Submitter supplied) Rodents respond to chronic high fat diet in at least two ways: some of them may readily gain body weight and become obese (termed obesity-prone), and others may not (termed obesity-resistant). An integrated approach of transcript and metabolic profiling of obesity-prone and obesity-resistant rats has been conducted, showing significantly different transcript and metabolic profiles in the two phenotypes. more...
    Organism:
    Rattus norvegicus
    Type:
    Expression profiling by array
    Dataset:
    GDS3677
    Platform:
    GPL4294
    8 Samples
    Download data:
    GEO (TXT)
    Series
    Accession:
    GSE11492
    ID:
    200011492
    3.

    Orotic acid induced fatty liver disease

    (Submitter supplied) A time course of orotic acid induced fatty liver disease. Kyoto and Wistar strain rats were exposed to orotic acid for days 1, 3 and 14. Controls are also included. Keywords = Wistar Keywords = Kyoto Keywords = orotic acid Keywords: time-course
    Organism:
    Rattus norvegicus
    Type:
    Expression profiling by array
    Dataset:
    GDS765
    Platform:
    GPL85
    18 Samples
    Download data:
    GEO
    Series
    Accession:
    GSE665
    ID:
    200000665
    4.
    Full record GDS765

    Fatty liver disease induced by orotic acid: time course

    Expression profiling of livers from inbred Kyotos and outbred Wistars fed a diet with 1% orotic acid to induce fatty liver disease. Profiles examined at various time points up to 14 days. Results used together with NMR spectroscopic analysis of the liver to identify perturbed metabolic pathways.
    Organism:
    Rattus norvegicus
    Type:
    Expression profiling by array, count, 2 agent, 2 strain, 4 time sets
    Platform:
    GPL85
    Series:
    GSE665
    18 Samples
    Download data:
    GEO
    DataSet
    Accession:
    GDS765
    ID:
    765
    5.

    The effect of mequindox on gene expression in rat liver tissue

    (Submitter supplied) Veterinary drug mequindox, 3-methyl-2-acethyl-quindoxaline-N-1,4-dioxide, belongs to a class of antibiotic and growth-prompting drug called quinoxalines that are often used in livestock and poultry industry. Previous researches focused on traditional toxicity. However, the effect of mequindox on endogenous metabolic profile remains unknown. We used microarrays to detail the global programme of gene expression underlying mequindox toxicity.
    Organism:
    Rattus norvegicus
    Type:
    Expression profiling by array
    Platform:
    GPL1355
    11 Samples
    Download data:
    GEO (CEL)
    Series
    Accession:
    GSE30935
    ID:
    200030935
    6.

    Transcriptome analysis of garlic induced hepatoprotection against alcoholic fatty liver

    (Submitter supplied) Alcohol induced fatty liver cause a dangerous health problem and is the major cause of morbidity and mortality worldwide. Garlic (Allium sativum) is documented to possess anti-fatty liver properties. However the exact molecular mechanisms are unknown. The main aim of this experiment is to elucidate the underlying pathways through which garlic ameliorates alcohol induced fatty liver. Dially disulfide and garlic oil were the garlic compounds used in this study. more...
    Organism:
    Mus musculus
    Type:
    Expression profiling by array
    Platform:
    GPL6885
    16 Samples
    Download data:
    GEO (TXT)
    Series
    Accession:
    GSE40334
    ID:
    200040334

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