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    Results: 20

    1.
    Full record GDS1687

    Low-shear modeled microgravity effect

    Analysis of wild type BY4743 cells grown in a low-shear modeled microgravity environment (LSMMG). LSMMG environment produced using a high aspect rotating vessel. Results provide insight into the response to the microgravity environment experienced during space flight.
    Organism:
    Schizosaccharomyces pombe; Saccharomyces cerevisiae
    Type:
    Expression profiling by array, transformed count, 2 age, 2 stress sets
    Platform:
    GPL2529
    Series:
    GSE4136
    12 Samples
    Download data:
    GEO
    2.

    Yeast Genomic Expression Patterns in Response to Low-Shear Modeled Microgravity

    (Submitter supplied) The goal of this study was to assess whether low shear-modeled microgravity (LSMMG) effects yeast genomic expression patterns using the powerful tool of whole genome microarray hybridization. We determined changes in the yeast model organism, Saccharomyces cerevisisae, when grown in LSMMG using the rotating High Aspect Ratio Vessel (HARV). A significant number of genes were up- or down-regulated by at least two fold in cells that were grown for 5 generations or 25 generations in HARVs. more...
    Organism:
    Schizosaccharomyces pombe; Saccharomyces cerevisiae
    Type:
    Expression profiling by array
    Dataset:
    GDS1687
    Platform:
    GPL2529
    12 Samples
    Download data:
    GEO
    Series
    Accession:
    GSE4136
    ID:
    200004136
    3.

    Response of Pseudomonas aeruginosa PAO1 to low shear modeled microgravity

    (Submitter supplied) Anticipating the risk for infectious disease during space exploration and habitation is a critical factor to ensure safety, health and performance of the crewmembers. As a ubiquitous environmental organism that is occasionally part of the human flora, Pseudomonas aeruginosa could pose a health hazard for the immuno-compromised astronauts. In order to gain insights in the behavior of P. aeruginosa in spaceflight conditions, two spaceflight-analogue culture systems, i.e. more...
    Organism:
    Pseudomonas aeruginosa; Pseudomonas aeruginosa PAO1
    Type:
    Expression profiling by array
    Platform:
    GPL84
    8 Samples
    Download data:
    GEO (CEL)
    Series
    Accession:
    GSE16970
    ID:
    200016970
    4.

    Gene expression and survival changes in Saccharomyces cerevisiae during suspension culture.

    (Submitter supplied) This study explores the connection between changes in gene expression and the genes that determine strain survival during suspension culture, using the model eukaryotic organism, Saccharomyces cerevisiae. The Saccharomyces cerevisiae homozygous diploid deletion pool, and the BY4743 parental strain were grown for 18 hours in a rotating wall vessel, a suspension culture device optimized to minimize the delivered shear. more...
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array
    Platforms:
    GPL90 GPL2544
    12 Samples
    Download data:
    GEO
    Series
    Accession:
    GSE2818
    ID:
    200002818
    5.

    Transcriptional response on ccw12 mutant from S. cerevisiae

    (Submitter supplied) Ccw12p is a cell surface mannoprotein required for cell wall stability. To investigate the compensation mechanism after CCW12 deletion we analysed the global gene expression in ccw12 mutant cells.
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array
    Platform:
    GPL90
    4 Samples
    Download data:
    GEO (CEL)
    Series
    Accession:
    GSE22649
    ID:
    200022649
    6.

    Nutrient-Regulated Antisense and Intragenic RNAs Modulate a Signal Transduction Pathway

    (Submitter supplied) The budding yeast Saccharomyces cerevisiae alters its gene expression profile in response to a change in nutrient availability. The PHO-system is a well-studied case in the transcriptional regulation responding to nutritional changes in which a set of genes (PHO genes) is expressed to activate phosphate (Pi) metabolism for adaptation to Pi-starvation. Pi-starvation triggers an inhibition of Pho85 kinase, leading to migration of unphosphorylated Pho4 transcriptional activator into the nucleus enabling expression of PHO genes. more...
    Organism:
    Saccharomyces cerevisiae
    Type:
    Genome binding/occupancy profiling by genome tiling array
    Platform:
    GPL3723
    8 Samples
    Download data:
    GEO (CEL)
    Series
    Accession:
    GSE13350
    ID:
    200013350
    7.

    JM43_Galactose_N2_AntimycinA

    (Submitter supplied) In previous temporal studies, we found the anaerobic response was biphasic when cells growing in galactose medium were shifted from aerobiosis to anaerobiosis, consisting of an acute, transitory phase (<60 min) followed by a more chronic but delayed phase (> 1 generation), but largely monophasic (delayed, chronic phase only) when cells were shifted in glucose medium. Gene network and functional analyses revealed the acute phase was comprised of genes associated with the retooling of metabolism (respiro-fermentative to strictly fermentative) and balancing energy supply and demand. more...
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array
    Platform:
    GPL1535
    227 Samples
    Download data:
    GEO
    Series
    Accession:
    GSE3706
    ID:
    200003706
    8.

    JM43 cells grown aerobically in galactose and treated with Antimycin A

    (Submitter supplied) In previous temporal studies, we found the anaerobic response was biphasic when cells growing in galactose medium were shifted from aerobiosis to anaerobiosis, consisting of an acute, transitory phase (<60 min) followed by a more chronic but delayed phase (> 1 generation), but largely monophasic (delayed, chronic phase only) when cells were shifted in glucose medium. Gene network and functional analyses revealed the acute phase was comprised of genes associated with the retooling of metabolism (respiro-fermentative to strictly fermentative) and balancing energy supply and demand. more...
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array
    Platform:
    GPL1535
    227 Samples
    Download data:
    GEO
    Series
    Accession:
    GSE3705
    ID:
    200003705
    9.

    Global mRNA expression analysis in myo1 delta strains of the budding yeast Saccharomyces cerevisiae

    (Submitter supplied) The Saccharomyces cerevisiae MYO1 gene encodes the myosin type II heavy chain (Myo1p), a protein required for normal cytokinesis in budding yeast. Deletion of the MYO1 gene prevents actomyosin-driven cytokinesis thereby activating an alternative mechanism that involves the synthesis of a remedial septum. Myo1p deficiency in yeast (myo1) also causes the formation of attached cells, abnormal budding patterns, formation of enlarged and elongated cells, increased osmotic sensitivity, delocalized chitin deposition, and increased chitin synthesis. more...
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array
    Platform:
    GPL884
    6 Samples
    Download data:
    GEO (TXT)
    Series
    Accession:
    GSE5931
    ID:
    200005931
    10.

    Differential control of Zap1-regulated genes in response to zinc deficiency in Saccharomyces cerevisiae

    (Submitter supplied) The Zap1 transcription factor is a central player in the response of yeast to changes in zinc status. Zap1 acts as both a positive and negative regulator of its target genes. We previously used transcriptome profiling with DNA microarrays to identify 46 potential Zap1 target genes in the yeast genome. In this study, we have used complementary methods to identify additional Zap1 target genes. With alternative growth conditions for the microarray experiments and a more sensitive motif identification algorithm, we have identified 31 new potential targets of Zap1 activation. more...
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array
    Platform:
    GPL7018
    4 Samples
    Download data:
    GEO (TXT)
    Series
    Accession:
    GSE11983
    ID:
    200011983
    11.

    Functional genomic analysis of a commercial wine strain of Saccharomyces cerevisiae under differing nitrogen conditions.

    (Submitter supplied) DNA microarray analysis was used to profile gene expression in a commercial isolate of Saccharomyces cerevisiae grown in a synthetic grape juice medium under conditions mimicking a natural environment for yeast: High-sugar and variable nitrogen conditions. The high nitrogen condition displayed elevated levels of expression of genes involved in biosynthesis of macromolecular precursors across the time course as compared to low-nitrogen. more...
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array
    Platforms:
    GPL3795 GPL66
    6 Samples
    Download data:
    GEO
    Series
    Accession:
    GSE4887
    ID:
    200004887
    12.

    whole reference dataset (cell wall chip)

    (Submitter supplied) Data processing included: 1. Filtering of those bad quality image spots (these includes alterations on the shape or hybridization) 2. Filtering of low intensity which was done flagging with -50 those spots whose feature intensity was lower in any of both channels than the average of the local background in the corresponding channel for all spots. However, those genes whose feature intensity in one channel was under the limit but in the other channel was 5 times over limit were considered as on-off genes and were not filtered. more...
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array
    Platforms:
    GPL1433 GPL1428
    20 Samples
    Download data:
    GEO
    Series
    Accession:
    GSE2105
    ID:
    200002105
    13.

    S. cerevisiae mutant with a constitutively activated Ras/cAMP pathway

    (Submitter supplied) Comparison of the transcriptomes of Saccharomyces cerevisiae wild type FY23 and a PDE2 deletion mutant DJ28. Keywords = PDE2 Keywords = Ras/cAMP pathway Keywords: other
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array
    Platform:
    GPL422
    10 Samples
    Download data:
    GEO
    Series
    Accession:
    GSE600
    ID:
    200000600
    14.

    Yeast Stress Response

    (Submitter supplied) We explored genomic expression patterns in the yeast Saccharomyces cerevisiae responding to diverse environmental transitions. DNA microarrays were used to measure changes in transcript levels over time for almost every yeast gene, as cells responded to temperature shocks, hydrogen peroxide, the superoxide-generating drug menadione, the sulfhydryl-oxidizing agent diamide, the disulfide-reducing agent dithiothreitol, hyper- and hypo-osmotic shock, amino acid starvation, nitrogen source depletion, and progression into stationary phase. more...
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array
    Datasets:
    GDS15 GDS16 GDS17 GDS18 GDS19 GDS20 GDS21 GDS30 GDS31 GDS33 GDS34 GDS35 GDS36 GDS108 GDS111 GDS112 GDS113 GDS115
    9 related Platforms
    156 Samples
    Download data:
    GEO
    Series
    Accession:
    GSE18
    ID:
    200000018
    15.
    Full record GDS115

    Amino acid and adenine starvation time course

    Cells grown in minimal medium lacking amino acids and adenine. Samples taken at 0, 0.5, 1, 2, 4 and 6 hours. Included as part of a detailed characterization of global expression programs triggered by environmental stress.
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array, log ratio, 5 time sets
    Platform:
    GPL54
    Series:
    GSE18
    5 Samples
    Download data:
    GEO
    16.
    Full record GDS113

    Dithiothrietol exposure time course (y14)

    2.5 mM dithiothrietol (DTT) added to culture and samples collected at several time points up to 480 minutes. Included as part of a detailed characterization of global expression programs triggered by environmental stress.
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array, log ratio, 7 time sets
    Platform:
    GPL54
    Series:
    GSE18
    7 Samples
    Download data:
    GEO
    17.
    Full record GDS112

    Heat shock from 30°C to 37°C time course

    Cultures shifted from 30°C to 37°C and samples collected at 0, 5, 15, 30 and 60 minutes. Included as part of a detailed characterization of global expression programs triggered by environmental stress.
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array, log ratio, 5 time sets
    Platform:
    GPL54
    Series:
    GSE18
    5 Samples
    Download data:
    GEO
    18.
    Full record GDS111

    Steady-state temperature (y14)

    Samples collected from cells grown continuously at 15°C, 17°C, 21°C, 25°C, 29°C, 33°C and 36°C. Included as part of a detailed characterization of global expression programs triggered by stress.
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array, log ratio, 7 temperature sets
    Platform:
    GPL54
    Series:
    GSE18
    8 Samples
    Download data:
    GEO
    19.
    Full record GDS108

    Menadione exposure time course

    Superoxide-generating drug menadione bisulphate (1 mM) added to culture and samples removed at several time points up to 160 minutes. Included as part of a detailed characterization of global expression programs triggered by environmental stress.
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array, log ratio, 9 time sets
    Platform:
    GPL64
    Series:
    GSE18
    9 Samples
    Download data:
    GEO
    20.
    Full record GDS36

    Heat shock from 29°C to 33°C time course

    Heat shock from 29°C to 33°C. Samples collected at 5, 15, 30 and 90 minutes. Included as part of a detailed characterization of global expression programs triggered by environmental stress.
    Organism:
    Saccharomyces cerevisiae
    Type:
    Expression profiling by array, log ratio, 4 time sets
    Platform:
    GPL56
    Series:
    GSE18
    4 Samples
    Download data:
    GEO

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