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Items: 2

1.

Tracheal Occlusion Modulates the Gene Expression Profile of the Medial Thalamus in Anesthetized Rats

(Submitter supplied) Conscious awareness of breathing requires the activation of higher brain centers. The sensation of breathing is believed to be a neural gating process. The thalamus provides the brain structure that could be responsible for the gating of respiratory sensory information to the cortex. It was reasoned that if the thalamus is the neural gate, then tracheal obstructions will modulate the gene expression profile of the thalamus. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL4135
8 Samples
Download data:
GEO (TXT)
Series
Accession:
GSE25153
ID:
200025153
2.

Tracheal occlusion conditioning in conscious rats modulates gene expression profile of medial thalamus

(Submitter supplied) The thalamus may be the critical brain area involved in sensory gating and the relay of respiratory mechanical information to the cerebral cortex for the conscious awareness of breathing. We hypothesized that respiratory mechanical stimuli in the form of tracheal occlusions would modulate the gene expression profile of the thalamus. Specifically, it was reasoned that conditioning to the respiratory loading would induce a state change in the medial thalamus consistent with a change in sensory gating and the activation of molecular pathways associated with learning and memory. more...
Organism:
Rattus norvegicus
Type:
Expression profiling by array
Platform:
GPL4135
8 Samples
Download data:
GEO (TXT)
Series
Accession:
GSE25152
ID:
200025152

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