GEO DataSets

(Submitter supplied) In these studies, we used splice variant-specific microarrays manufactured by the ExonHit company ( www.exonhit.com) on the Affymetrix platform. The goal was to identify splice isoforms whose expression is altered in whole blood of early-stage Parkinson’s disease patients compared to healthy and neurodegenerative disease controls. The study included 19 cases of Parkinson’s disease (PD) samples, 4 of multiple system atrophy (MSA), 4 progressive supranuclear palsy (PSP) and 10 healthy controls. more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Platform:

GPL7884

39 Samples

Download data: CEL

(Submitter supplied) Parkinson’s disease (PD) progresses relentlessly and affects five million people worldwide. Laboratory tests for PD are critically needed for developing treatments designed to slow or prevent progression of the disease. We performed a transcriptome-wide scan in 105 individuals to interrogate the molecular processes perturbed in cellular blood of patients with early-stage PD. The molecular marker here identified is strongly associated with risk of PD in 66 samples of the training set (third tertile cross-validated odds ratio of 5.7 {P for trend 0.005}). more...

Organism:

Homo sapiens

Type:

Expression profiling by array

Dataset:

GDS2519

Platform:

GPL96

105 Samples

Download data: CEL

Analysis of blood of 50 patients predominantly with early-stage Parkinson’s disease (PD). Results provide insight into the molecular processes perturbed in the cellular blood of patients with early-stage PD.

Organism:

Homo sapiens

Type:

Expression profiling by array, count, 3 disease state sets

Platform:

GPL96

Series:

GSE6613

105 Samples

Download data: CEL