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Items: 4

1.

Circulating plasma MicroRNA in patients with active acromegaly

(Submitter supplied) Plasma microRNAs were quantified by next-generation sequencing (NGS) to evaluate the difference in circulating microRNAs (miRNAs) associated with chronic growth hormone overproduction in adults
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
24 Samples
Download data: TSV
Series
Accession:
GSE174146
ID:
200174146

2.

Expression data from peripheral blood from healthy and predisposed individuals

(Submitter supplied) Characterization of the underlying genetic defects in patients with a rare and peculiar phenotype is challenging. Here we have utilized whole genome expression profiling, and identified a homozygous germline mutation in the DDB2 gene in a patient with several facial tumors. The feasibility of using blood derived RNA, diminishing costs of the technology, and the limited number of samples needed provide this approach a powerful new tool that may substantially aid in such gene identification efforts. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL570
15 Samples
Download data: CEL, EXP
Series
Accession:
GSE6351
ID:
200006351

PubMed Full text in PMC Similar studies Analyze with GEO2R

3.

Expression data from whole blood

(Submitter supplied) While identification of genes mutated in high penetrance tumor predisposition syndromes has been a success story, much less progress has been made in characterizing the genetic basis of low penetrance tumor susceptibility. Combining recently introduced chip-based technologies with traditional genealogy work we have identified inactivating germline mutations in patients with pituitary adenoma predisposition (PAP). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Dataset:
GDS2432
Platform:
GPL570
16 Samples
Download data: CEL, EXP
Series
Accession:
GSE4488
ID:
200004488

PubMed Similar studies Analyze with GEO2R

4.
Full record GDS2432

Pituitary adenoma predisposition: whole blood

Analysis of whole blood from individuals with pituitary adenoma predisposition. Pituitary adenomas are common benign neoplasms characterized by oversecretion of growth hormone, leading to acromegaly. Results provide insight into the molecular basis of pituitary adenomas.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 2 disease state sets
Platform:
GPL570
Series:
GSE4488
16 Samples
Download data: CEL, EXP
DataSet
Accession:
GDS2432
ID:
2432

PubMed Similar studies GEO Profiles Analyze DataSet

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db=gds|term=%22disease%20state%22[All%20Fields]%20AND%20%22Homo%20Sapiens%22[porgn]%20AND%20(%22Acromegaly%22[MeSH%20Terms]%20OR%20%22Acromegaly%22[All%20Fields])%20AND%20(%22gds%22[Filter]%20OR%20%22gse%22[Filter]%20OR%20%22gsm%22[Filter])%20AND%20(%22Expression%20profiling%20by%20array%22[Filter]%20OR%20Expression%20profiling%20by%20high%20throughput%20sequencing[Filter])|query=1|qty=2|blobid=MCID_6628141e862bea0a3f8646e6|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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  • "disease state"[All Fields] AND "Homo Sapiens"[porgn] AND ("Acrom... (4)
    "disease state"[All Fields] AND "Homo Sapiens"[porgn] AND ("Acromegaly"[MeSH Terms] OR "Acromegaly"[All Fields]) AND ("gds"[Filter] OR "gse"[Filter] OR "gsm"[Filter]) AND ("Expression profiling by array"[Filter] OR Expression profiling by high throughput sequencing[Filter])
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