H3K4me3 - Human neuroblastoma epithelial cell, SH-SY5Y cell line, neuroblastoma, child
ESX000000859 - Experiment
Summary
Histone modification H3K4me3 assayed by ChIP-seq in Homo sapiens, cell line derived from a metastatic neuroblastoma and isolated from bone marrow. From Kleine-Kohlbrecher, et al. 2010.
Keywords: histone modification, H3K4me3
Genome track
| Track name: | H3K4me3 in SH-SY5Y |
| Genome release: | GRCh37 (hg19) |
| Accession number: | NA000001311.1 |
| File type: | WIG |
| File: | ESX000000859.wig.gz |
| Note: |
1 - Data were not submitted in wig format. Tracks were generated by NCBI from submitted raw data. See how. |
DownloadView on Genome
Experimental details
| Feature: | H3K4me3 |
| Antibody: | Abcam ab1012 |
| Technique: | ChIP-seq |
| Instrument: | Illumina Genome Analyzer II |
| Assay Type: | histone modification |
Sample
Human neuroblastoma epithelial cell, SH-SY5Y cell line, neuroblastoma, child
Homo sapiens, cell line derived from a metastatic neuroblastoma and isolated from bone marrow. Features assayed include H3K4me3, PHF8, ZNF711. From Kleine-Kohlbrecher, et al. 2010.
Study
Genome-wide mapping of H3K4me3 and of PHF8 and ZNF711 binding sites in SH-SY5Y cells
This study examines genome wide binding sites for the potential XLMR genes PHF8 and ZNF711 in the neuroblastoma cell line SH-SY5Y using antibodies specific for PHF8 and ZNF711 and correlated this with binding pattern of H3K4me3.
Data submission
Genome-wide mapping of H3K4me3 and of PHF8 and ZNF711 binding sites in SH-SY5Y cells
We analyzed the genome wide binding sites for the potential XLMR genes PHF8 and ZNF711 in the neuroblastoma cell line SH-SY5Y using antibodies specific for PHF8 and ZNF711 and correlated this with binding pattern of H3K4me3. The total number of peaks detected for PHF8 based on 9.8 million sequenc...
Biotech Research and Innovation Centre/University of Copenhagen. Public on: Mar 08 2010
GSM518558 - GEOSRA
Reference
A functional link between the histone demethylase PHF8 and the transcription factor ZNF711 in X-linked mental retardation.
Kleine-Kohlbrecher D, et al. Mol Cell. 2010 Apr 23;38(2):165-78. - Similar
PMID: 20346720 -
Citation