H3K36me3 - Human breast cancer epithelial cell, MDA-MB-231 cell line, mammary gland, adenocarcinoma, adult
ESX000000117 - Experiment
Genome track
| Track name: | H3K36me3_ChIPSeq |
| Genome release: | GRCh37 (hg19) |
| Accession number: | NA000000603.0 |
| File type: | WIG |
| File: | ESX000000117.wig.gz |
| Note: |
1 - Data were not submitted in wig format. Tracks were generated by NCBI from submitted raw data. See how. |
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Experimental details
| Feature: | H3K36me3 |
| Antibody: | Abcam 9050 |
| Technique: | ChIP-seq |
| Instrument: | Illumina Genome Analyzer II |
| Assay Type: | histone modification |
Sample
Human breast cancer epithelial cell, MDA-MB-231 cell line, mammary gland, adenocarcinoma, adult
Homo sapiens. Features assayed include DNA methylation, H3K36me3, H3K4me2. From Hodges, et al. 2009.
Study
High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing
Global DNA methylation is examined by bisulfite-seq in both human primary and cancer cell lines. H3K4me2 and H3K36me3 are also examined.
Data submission
High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing
DNA methylation stabilizes developmentally programmed gene expression states. Aberrant methylation is associated with disease progression and is a common feature of cancer genomes. Presently, few methods enable quantitative, large-scale, single-base resolution mapping of DNA methylation states in ...
Cold Spring Harbor Laboratory. Public on: Jul 08 2009
GSM425485 - GEOSRA
Reference
High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing.
Hodges E, et al. Genome Res. 2009 Sep;19(9):1593-605. - Similar
PMID: 19581485 -
Citation