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    DNA methylation - Human fibroblast, CHP-SKN-1 cell line, dermis

    ESX000000114 - Experiment

    Summary

    DNA methylation assayed by bisulfite-seq in Homo sapiens. From Hodges, et al. 2009.

    Keyword: DNA methylation

    Genome track

    Track name:CHPSKN1_Biulfite_seq
    Genome release:GRCh37 (hg19)
    File type:WIG
    File:ESX000000114.wig.gz
    Note:

    1 - Data were not submitted in wig format. Tracks were generated by NCBI from submitted raw data. See how.

    DownloadView on Genome

    Experimental details

    Feature: DNA methylation
    Technique: bisulfite-seq
    Instrument: Illumina Genome Analyzer II
    Assay Type: DNA methylation

    Study

    High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing

    Global DNA methylation is examined by bisulfite-seq in both human primary and cancer cell lines. H3K4me2 and H3K36me3 are also examined.

    Data submission

    High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing

    DNA methylation stabilizes developmentally programmed gene expression states. Aberrant methylation is associated with disease progression and is a common feature of cancer genomes. Presently, few methods enable quantitative, large-scale, single-base resolution mapping of DNA methylation states in ...

    Cold Spring Harbor Laboratory. Public on: Jul 08 2009

    GSM425461 - GEOSRA

    Reference

    High definition profiling of mammalian DNA methylation by array capture and single molecule bisulfite sequencing.

    Hodges E, et al. Genome Res. 2009 Sep;19(9):1593-605. - Similar

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