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    H3K9me1 - Human fibroblast, IMR90 cell line, lung, fetus

    ESX000000580 - Experiment

    Summary

    Histone modification H3K9me1 assayed by ChIP-seq in Homo sapiens. Data from the Roadmap Epigenomics project.

    Part of Reference epigenome - IMR90 Cell Line - ERE004

    Keywords: histone modification, H3K9me1

    Genome track

    Track name:renlab.H3K9me3.IMR90-02.01.hg19.level.2
    Genome release:
    Accession number:NA000004991.1
    File type:WIG
    File:

    DownloadView on Genome

    Experimental details

    Feature: H3K9me1
    Antibody: Abcam 8896
    Technique: ChIP-seq
    Instrument: Illumina Genome Analyzer II
    Assay Type: histone modification

    Quality Metrics

    FindPeaks Score: 0.3807
    FindPeaks Percentile: 93
    Hotspot Score: 0.1913
    Hotspot Percentile: 64
    IROC Score: 0.8428
    IROC Percentile: 56
    Poisson Score: 0.4709
    Poisson Percentile: 80

    Sample

    Human fibroblast, IMR90 cell line, lung, fetus

    Homo sapiens. Features assayed include DNA methylation, Digital Genomic Footprinting, H2A.Z, H2AK5ac, H2AK9ac, H2BK120ac, H2BK12ac, H2BK15ac, H2BK20ac, H2BK5ac, H3K14ac, H3K18ac, H3K23ac, H3K27ac, H3K27me3, H3K36me3, H3K4ac, H3K4me1, H3K4me2, H3K4me3, H3K56ac, H3K79me1, H3K79me2, H3K9ac, H3K9me1, H3K9me3, H4K20me1, H4K5ac, H4K8ac, H4K91ac, chromatin accessibility, gene expression, small RNA analysis. Data from the Roadmap Epigenomics project.

    Study

    Human Reference Epigenome Mapping Project

    Characterization of the reference epigenome in humans by use of ChIP-Seq in a diverse panel of ES cells, tissue stem cells, reprogrammed stem cells, primary cells and tissues. Histone modifications and DNA methylation will be examined.

    Data submission

    UCSD Human Reference Epigenome Mapping Project

    The human embryonic stem cells (hESCs) are a unique model system for investigating the mechanisms of human development due to their ability to replicate indefinitely while retaining the capacity to differentiate into a host of functionally distinct cell types. In addition, these cells could be pote...

    University of California, San Diego. Public on: Aug 03 2009

    GSM521913 - GEOSRA

    Reference

    The NIH Roadmap Epigenomics Mapping Consortium.

    Bernstein BE, et al. Nat Biotechnol. 2010 Oct;28(10):1045-8. - Similar

    Distinct epigenomic landscapes of pluripotent and lineage-committed human cells.

    Hawkins RD, et al. Cell Stem Cell. 2010 May 7;6(5):479-91. - Similar

    Human DNA methylomes at base resolution show widespread epigenomic differences.

    Lister R, et al. Nature. 2009 Nov 19;462(7271):315-22. - Similar

    Hotspots of aberrant epigenomic reprogramming in human induced pluripotent stem cells.

    Lister R, et al. Nature. 2011 Mar 3;471(7336):68-73. - Similar

      Supplemental Content

      NIH Roadmap Epigenomics

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