|
Clinical Queries Filter Table |
| Entrez | PubMed | Nucleotide | Protein | Genome | Structure | OMIM | PMC | Journals | Books |
Clinical Queries using Research Methodology Filters
Medical Genetics Search Filters
| Category | Optimized For | Sensitive/ Specific | PubMed Equivalent |
|---|---|---|---|
| therapy | sensitive/broad | 99%/70% | ((clinical[Title/Abstract] AND trial[Title/Abstract]) OR clinical trials[MeSH Terms] OR clinical trial[Publication Type] OR random*[Title/Abstract] OR random allocation[MeSH Terms] OR therapeutic use[MeSH Subheading]) |
| specific/narrow | 93%/97% | (randomized controlled trial[Publication Type] OR (randomized[Title/Abstract] AND controlled[Title/Abstract] AND trial[Title/Abstract])) | |
| diagnosis | sensitive/broad | 98%/74% | (sensitiv*[Title/Abstract] OR sensitivity and specificity[MeSH Terms] OR diagnos*[Title/Abstract] OR diagnosis[MeSH:noexp] OR diagnostic * [MeSH:noexp] OR diagnosis,differential[MeSH:noexp] OR diagnosis[Subheading:noexp]) |
| specific/narrow | 64%/98% | (specificity[Title/Abstract]) | |
| etiology | sensitive/broad | 93%/63% | (risk*[Title/Abstract] OR risk*[MeSH:noexp] OR risk *[MeSH:noexp] OR cohort studies[MeSH Terms] OR group*[Text Word]) |
| specific/narrow | 51%/95% | ((relative[Title/Abstract] AND risk*[Title/Abstract]) OR (relative risk[Text Word]) OR risks[Text Word] OR cohort studies[MeSH:noexp] OR (cohort[Title/Abstract] AND stud*[Title/Abstract])) | |
| prognosis | sensitive/broad | 90%/80% | (incidence[MeSH:noexp] OR mortality[MeSH Terms] OR follow up studies[MeSH:noexp] OR prognos*[Text Word] OR predict*[Text Word] OR course*[Text Word]) |
| specific/narrow | 52%/94% | (prognos*[Title/Abstract] OR (first[Title/Abstract] AND episode[Title/Abstract]) OR cohort[Title/Abstract]) | |
| clinical prediction guides | sensitive/broad | 96%/79% | (predict*[tiab] OR predictive value of tests[mh] OR scor*[tiab] OR observ*[tiab] OR observer variation[mh]) |
| specific/narrow | 54%/99% | (validation[tiab] OR validate[tiab]) |
The Clinical Queries search filters are based on the work
of Haynes RB et al.
| Category | PubMed Equivalent |
|---|---|
| Diagnosis | (Diagnosis AND Genetics) |
| Differential Diagnosis | (Differential Diagnosis[MeSH] OR Differential Diagnosis[Text Word] AND Genetics) |
| Clinical Description | (Natural History OR Mortality OR Phenotype OR Prevalence OR Penetrance AND Genetics) |
| Management | (therapy[Subheading] OR treatment[Text Word] OR treatment outcome OR investigational therapies AND Genetics) |
| Genetic Counseling | (Genetic Counseling OR Inheritance pattern AND genetics) |
| Molecular Genetics | (Medical Genetics OR genotype OR genetics[Subheading] AND genetics) |
| Genetic Testing | (DNA Mutational Analysis OR Laboratory techniques and procedures OR Genetic Markers OR diagnosis OR testing OR test OR screening OR mutagenicity tests OR genetic techniques OR molecular diagnostic techniques AND genetics) |
| All | ((Diagnosis AND genetics) OR (Differential Diagnosis[MeSH] OR Differential Diagnosis[Text Word] AND genetics) OR (Natural History OR Mortality OR Phenotype OR Prevalence OR Penetrance AND genetics) OR (therapy[Subheading] OR treatment[Text Word] OR treatment outcome OR investigational therapies AND genetics) OR (Genetic Counseling OR Inheritance pattern AND genetics) OR (Medical Genetics OR genotype OR genetics[Subheading] AND genetics) OR (DNA Mutational Analysis OR Laboratory techniques and procedures OR Genetic Markers OR diagnosis OR testing OR test OR screening OR mutagenicity tests OR genetic techniques OR molecular diagnostic techniques AND genetics)) |
The genetics searches were developed in conjunction with the staff of GeneReviews: Genetic Disease Online Reviews at GeneTests, University of Washington, Seattle.