PubMed Central
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PubMed Central Help
Updated:  June 22, 2004

PubMed Central Searching
PubMed Central is a digital archive of life sciences journal literature managed by the National Center for Biotechnology Information (NCBI) at the U.S. National Library of Medicine (NLM). It is not a journal publisher. Access to PubMed Central (PMC) is free and unrestricted. Learn more about how publishers can participate in PMC.

Databases on the black menu bar are links to the other NCBI resources.

To search PubMed Central enter search terms in the query box, and press the Enter key or click Go.  The Features bar directly beneath the query box provides access to additional search options. The PubMed Central query box and Features bar are available from every screen, so you don't need to return to the homepage to enter a new search.

You may enter one or more terms (e.g., scientific collaboration trends) in the query box; PubMed Central automatically combines (ANDs) significant terms together using automatic term mapping. The terms are searched in various fields of the record. If your search includes Boolean operators (AND, OR, NOT), they must be in upper case, e.g., "acupuncture OR massage".

Once you click Go, PubMed Central will display your search results.  The query box displays your search terms as you entered them.

You can modify your current search by adding or eliminating terms in the query box or in Details.  If you applied Limits, the check box next to Limits will be marked, and a listing of your limit selections will be displayed. To turn off the existing limits, uncheck the Limits checkbox before running your next search.

Author
To search by an author's name, enter the name in the format of last name plus initials (no punctuation), e.g., smith a black dh. PubMed Central automatically truncates the author's name to account for varying initials and designations such as Jr. or 2nd. A name entered using this format will search in the author field. If only the author's last name is entered, PubMed Central searches the name in All Fields, except when the author name is found in the MeSH (National Library of Medicine's Medical Subject Headings) Translation table (e.g., Yang will search as Yin-Yang [MeSH] or Yang [Text Word].) To search for an author in the author field when only the last name is available qualify the author with the author search field tag [au], e.g., "yang [au]".

Note:

  1. Use double quotes around the author's name with the author search field tag [au] to turn off the automatic truncation, e.g., "smith k" [au].
  2. Use the [au] search tag if the author name is also a subject term, e.g., moran a [au]. The unqualified phrase moran a will search as "moran A"[Substance Name] OR moran a[Text Word].
Journal Titles
You may search by the full journal title, e.g., molecular biology of the cell; the MEDLINE abbreviation, e.g., mol biol cell; or the ISSN number (standardized international code), e.g., 1059-1524. See the Journal Database for the full journal titles.

Note:

  1. If a journal is also a MeSH term (e.g., Critical Care), PubMed Central searches the unqualified term as MeSH. Qualify the journal title with the Journal Title search field tag, e.g., critical care [ta], to search for the journal.
  2. Qualify single word journal titles using the Journal Title search field tag, e.g., scanning [ta], as PubMed Central will search unqualified single journal titles as MeSH terms (if applicable) or in All Fields.
  3. If a journal includes parentheses or brackets, enter the name without the parentheses or brackets, e.g., search J Hand Surg [Am] as j hand surg am.
Automatic Term Mapping
Unqualified terms that are entered in the query box are matched (in this order) against a MeSH (Medical Subject Headings) Translation Table, a Journals Translation Table, a Phrase List, and an Author Index. PubMed Central ignores stopwords from search queries.

1. MeSH and Organism Translation Tables
The MeSH translation table contains MeSH Terms, the See-Reference mappings (also known as entry terms) for MeSH Heading terms, MeSH Subheadings, terms derived from the Unified Medical Language System (UMLS) that have equivalent synonyms or lexical variants in English, and the Supplementary Concept (Substance) Names and their synonyms. If a match is found in this translation table, the term will be searched as MeSH and as a Text Word. For example, if you enter "vitamin h" in the query box, PubMed Central will translate this search to: ("Biotin"[MeSH Terms] OR vitamin h[Text Word]) - vitamin h is an entry term for the MeSH term Biotin.

The Organism translation table contains the scientific and common names for the organisms associated with protein and nucleotide sequences.

Note:

Click on Details to verify how your terms are translated.
2. Journals Translation Table
The Journals translation table contains the full journal title, the MEDLINE abbreviation, and the ISSN number. These map to the journal abbreviation that is used to search journals in PubMed Central. For example, if you enter the journal title, breast cancer research, in the PubMed Central query box, it will translate to: Breast Cancer Res"[Journal].

3. Phrase List
If no match is found, PubMed Central consults a Phrase List. Phrases on this list are generated from MeSH, the UMLS, and Supplementary Concept Substance Names, e.g., "multidrug transporter".

4. Author Index
If the phrase is not found in the above tables or list and is a word followed by one or two letters, then PubMed Central checks the Author index.

If no match is found?
PubMed Central breaks apart the phrase and repeats the above automatic term mapping process until a match is found. If there is no match, the individual terms will be combined (ANDed) and searched in All Fields.

See Also:

Truncation (finding all terms that begin with a given text string)
Place an asterisk at the end of a term to search for all terms that begin with that word; for instance flavor* will find all terms that begin with the letters flavor, e.g., flavored, flavorful, flavoring, etc. PubMed Central searches for the first 150 variations of a truncated term. If a truncated term, e.g., tox*, produces more than 150 variations, PubMed Central displays the warning message shown below.

Wildcard search for 'term*' used only the first 150 variations. Lengthen the root word to search for all endings.

Note:

Truncation turns off automatic term mapping and the automatic explosion of a MeSH term. For example, heart attack* will not map to the MeSH term, Myocardial Infarction or include any of the more specific terms, e.g., Myocardial Stunning; Shock, Cardiogenic.
Phrase Searching (specifying a phrase in a search)
PubMed Central does not actually perform adjacency searching but uses a list of recognized phrases against which search terms are matched. Many phrases are recognized by the automatic term mapping feature. For example, if you enter poison ivy, PubMed Central recognizes these two words as a phrase and searches it as one search term. If your phrase is not recognized, you can instruct PubMed Central to check for a phrase in the Index of searchable terms. This is done by entering the phrase in quotes, e.g., "single cell".

Note:

  1. If your search phrase is not on the list of recognized phrases, then the double quotes are ignored, and the phrase is processed using automatic term mapping. Your phrase may actually appear in the record data yet not be on the phrase list.
  2. When you enclose a phrase in double quotes, PubMed Central will not perform automatic term mapping. For example, "health planning" will include citations that are indexed to the MeSH term, Health Planning, but will not include the more specific terms, e.g., Health Care Rationing, Health Care Reform, Health Plan Implementation and so on, that are typically included with the automatic MeSH mapping.
For Additional Information on Search Strategies, see also: Additional Search Rules Boolean and Syntax
  1. Boolean operators, AND, OR, NOT must be entered in upper case, e.g., vitamin c OR zinc.
  2. PubMed Central processes all Boolean connectors in a left-to-right sequence. You can change the order by enclosing individual concepts in parentheses. The terms inside the set of parentheses will be processed as a unit and then incorporated into the overall strategy, e.g., common cold AND (vitamin c OR zinc).
  3. If PubMed Central finds a phrase within a search strategy string that uses unqualified terms, it will automatically search the terms as a phrase rather than combining the individual words. For example, if you enter multidrug transporter in the query box, PubMed Central will search "multidrug transporter" as a phrase. If you do not want this automatic phrase parsing, enter each term separated by the Boolean operator AND, e.g., multidrug AND transporter.
  4. Follow the search and syntax rules to enter search terms, specify the search field to be searched and the Boolean operators in your search statement:
search term [tag] BOOLEAN OPERATOR search term [tag]

Examples of Boolean Search Statements:

Find citations on DNA that were authored by C Campbell:

dna AND campbell c

Find articles that deal with the effects of heat or humidity on multiple sclerosis, where
these words appear in all fields in the citation:

(heat OR humidity) AND multiple sclerosis

Possessive Names as Part of Terms
If you are searching for a term named for an individual, be sure to include the full name of the term, e.g., "crohn's disease" or "coon's technique". The possessive form is not required, i.e., "crohn disease", can be used. Alternatively, use the non-possessive form of the term with the [tw] search tag, e.g., "hodgkin [tw]".

Search Field Qualification
Terms can be qualified using Search Field tags.

  1. Add the search tag after the term, e.g., "neoplasms [mh]"
  2. Search field tags must be enclosed in square brackets, "[mh]"
Dates & Date Ranging
Dates or date ranges must be entered using the format YYYY/MM/DD [date field], e.g., "1997/10/06 [pdat]". The month and day are optional, e.g., "1997 [pmcdat]" or "1997/03 [pdate]".

To enter a date range, insert a colon (:) between each date, e.g., "1993:1995 [dp]" or
"1997/01:1997/06 [pmcdat]".

Date Fields:

Date of Publication [pdat]
PMC Live Date [pmcdat] The date the citation first entered PubMed Central.
Electronic Publication Date [epubdat] The date of electronic publication.

Date ranging is also available from the fill-in-the-blank selection on the Limits screen.

Cookies
What is a "cookie"?
A "cookie" is information sent by a web site server (e.g., PubMed Central) to your computer. In the case of PubMed Central, it is information about your interactions that may be needed to perform a later function. Cookies allow PubMed Central to provide more interactive features such as Preview/Index, Clipboard, History, and the Cubby. Cookies placed by PubMed Central are removed from your computer after a set time period. There are many web sites that provide information about cookies. Netscape provides technical information.

How can I tell if my system accepts cookies?
Cookie-dependent features of PubMed Central include Preview/Index, History, Clipboard, and the Cubby. To use these features, your system must be able to accept cookies. If you still have problems using cookie-dependent features of PubMed Central even after enabling cookies possible reasons may include:

  1. Cookies are blocked by your provider or institution: Check with your Internet provider and/or the system administrator at your institution to see if cookies can be accepted. Even if you have them enabled in your web browser, if they are blocked by your provider or institution (e.g., by a firewall, proxy server, etc.), cookie-dependent features of PubMed Central won't work.
  2. Your computer's date & time settings are incorrect: Check your computer's time settings to ensure that they are correct.

Features Bar
Limits
Click Limits from the Features bar to limit your search to a specific search field. Limits allows you to restrict to articles published in a specific journal or by a specific author. You can also limit your search by Publication Date, Electronic Publication Date, or PMC Date.

Note:

If you select a limit and either run a search or move to another screen, a check will appear in a box next to Limits on the Features bar to indicate that limits have been selected. If you then run a search, the limits in effect will appear in the yellow bar above the Display button. To turn off the limits before you run your next search, uncheck the box.
Field Selection
You may limit your search terms to a specific search field. All Fields is the default for searching. To select a specific field, click the All Fields pull-down menu and select a search field.

See also:

Preview/Index
Use the Preview/Index feature to: To preview the number of results before displaying the citations, type your term(s) in the query box and click Preview. Preview displays the number of citations in your search results. To refine your search strategy, add another term to the existing term(s) in the query box and click Preview. The additional terms will be combined with the existing terms, and the new search with the new number of citations will display. Continue adding terms until your strategy is complete. To display your results, click on the result number (hypertext) in the Preview display.

To search for terms from specific search fields use the Add Term(s) to Query text box. Select a search field from the All Fields pull-down menu and enter a term in the text box. Click AND, OR, or NOT to add the term to the query box with the appropriate search field tag, or click Preview to see the number of results.

The available Boolean operators are:

Intersection (AND) - only those citations that contain selected terms.
Union (OR) - citations that contain at least one of the selected terms.
Difference (NOT) - exclude citations with the selected term.

You can also use Index to select from a list of terms within a search field. Select a search field from the All Fields pull-down menu, enter a term in the box, and click Index. PubMed Central displays an alphabetic list of terms in the Index for the selected search field. The number of citations in PubMed Central that contain the term appears in parentheses to the right of the term. You can scroll up or down the list, or click Up or Down to move along in the Index.

Highlight a term by clicking on it. Then click the appropriate operator, AND, OR, NOT. The selected term will be added to the query box. To OR together multiple terms from an Index display and then add (or AND) them to your search, click on each term while holding down the Ctrl-key (PC) or the Command-key (Mac). When all the terms you want are highlighted, click the connector AND to add the terms (ORed together) to the query.

You may then continue to add additional terms from other search fields. Once your strategy is complete, click Preview to see the number of results, or click Go to display the citations.

Note:

  1. Preview/Index displays the last three queries from History. Use History to review up to the last 100 queries.
  2. PubMed Central processes all Boolean operators left to right. To change this order enclose search terms to be processed first in parentheses, e.g., common cold AND (vitamin c OR zinc). You may edit (e.g., add parentheses) in any query box. PubMed Central will automatically OR (and add parentheses) for multiple terms selected from the Index.
  3. Preview uses cookies to keep a history of your searches. In order for you to use this feature your web browser must be set to accept cookies.
History
PubMed Central holds all your search strategies and results in History. You can see your search History by clicking on History from the Features bar. History is only available after you run your first search. History lists and numbers your searches in the order in which they were run. History displays the search number, your search query, the time of search, and the number of citations in your results. To view the results from a search, click on the number of results.

You can combine searches or add additional terms to an existing search by using the pound sign (#) before the search number, e.g., "#2 AND #6", or "#3 AND (drug therapy OR diet therapy)". Once you have entered a revised search strategy in the query box, click Go to view the search results. Click Clear History to remove all searches from the History screen and the Preview/Index screen.

Note:

  1. The maximum number of queries held in History is 100. Once the maximum number is reached, PubMed Central will remove the oldest search from the History to add the most current search.
  2. The Search History will be lost after one hour of inactivity on PubMed Central or any of the other Entrez databases. The Clear History button in History will also clear the Preview/Index history information.
  3. PubMed Central will move a search statement number to the top of the History if the new search is the same as a previous search.
  4. A separate Search History will be kept for each of the Entrez databases although the search statement numbers will be assigned sequentially for all databases.
  5. PubMed Central uses cookies to keep a history of your searches. To use this feature, your web browser must be set to accept cookies.
  6. History search numbers may not be continuous because some numbers are assigned to intermediate processes such as displaying a citation in another format.


Clipboard
The Clipboard gives you a place to collect selected citations from one search or several searches. After you add citations to the Clipboard, you may then want to use the print, save, or order buttons. The maximum number of items that can be placed in the Clipboard is 500. Once you have added items to the Clipboard, you can click on Clipboard from the Features bar to view your selections.

Add to Clipboard
To place an item in the Clipboard, click on the check box to the left of the citation, select Clipboard from the Send to pull-down menu, and then click the Send to button. Once you have added a citation to the Clipboard, the record number color will change to green.

Note:

  1. If you select Clipboard from the Send to menu without selecting citations using the check box, PubMed Central will add all (up to 500 citations) of your search results to the Clipboard.
  2. The Clipboard will be lost after 1 hour of inactivity on PubMed Central or any of the other Entrez databases.
  3. PubMed Central uses cookies to add your selections to the Clipboard. To use this feature, your web browser must be set to accept cookies.
  4. Citations in the Clipboard are represented by the search number #0 which may be used in Boolean search statements.
Saving from the Clipboard
Citations are initially displayed in the summary format in the relevancy order. Use Sort to change the order. You can select all or individual citations to display or save in one of the citation display formats. Select the desired format from the pull-down menu, click Save to save your selections to a file, or use the Print feature of your web browser to print the citations. Printing from your web browser will only print the information and citations listed on the web page. You may also display citations as plain text without the sidebar menu and toolbars by clicking the Text button.

Note:

Your results may be on more than one page. PubMed Central will retain your selections from all pages of your results. To mark specific citations to save, click on the check box to the left of each citation and continue to page through your results. Use Save to save all the selected citations to a file.
See Also: Deleting Citations from the Clipboard
You can delete citations from your Clipboard. To mark citations for deletion, click on the check box to the left of the citation and click Clip Remove. To empty your entire Clipboard, do not mark any of the citations, simply click "Clip Remove".

Details
Details lets you view your search strategy as it was translated using automatic term mapping and search rules and syntax. Also, from Details, you can save a search query or edit the search query and resubmit it. Details also includes error messages and notes.

Editing Your Search in Details
The Query box shows the actual search strategy and syntax used to run the search. Beneath this box, the Result number hyperlink displays the total number of matches for the current search. To return to the current search results screen, click this link or use the "Back" function of your Web browser. The Translations area details how each term was translated, and the User Query area shows the search terms as you entered them in the query box.

To edit the search strategy in the Query box, click in the box to add or delete terms and then click Search.

Saving a Search Strategy from Details
From the Details window, use the URL button to display the current search strategy as a URL and then bookmark the URL for future use.

To save a search strategy:

  1. From the Details window, click on URL. You will return to the search results screen. The translated search strategy will be displayed in the query box, and this search strategy will also be embedded as part of the URL.
  2. Next, use your Web browser's bookmark function to save the URL as a bookmark. After saving the bookmark, you may want to use your Web browser's edit functions to rename the bookmark.
Note:
Searches that were created using a search statement number in History (e.g., "#1 or #2 AND human[mh]") should not be saved using the URL feature, as the search statements represented by these numbers are lost when History is deleted.
Documents
Display
PubMed Central displays your search results in relevancy order by batches - the default is 20 citations per page.

The Show pull-down menu allows you to change the number of citations displayed on a single page up to a maximum of 500 items. To do this:

To move to a specific result Page enter the page number in the Page box and click the Page button. Click the Previous or Next hyperlinks to move back or forward a page. The current page number is displayed in the Page box.

PubMed Central citations are initially displayed in a summary format. You can choose to display other formats:

Text
You may display citations as plain text without the sidebar menu and toolbars by selecting Text from the Send to pull-down menu. To display citations in a different format, choose the desired format from the display pull-down menu, and select Text. To return to your results in PubMed, use your browser's back button.

Display Order
Citations in PubMed Central are displayed in relevancy order.

Sort
To change the citation order display from relevancy select a sort field from the Sort pull-down menu and click Display. Publication Date sorts the most recent citations first, the secondary sort is journal. Electronic Publication Date sorts by most recent online publication date. Journal sorts A to Z, the secondary sort is publication date. PMC Live Date sorts by date available online.

Save
The Save function creates a text file of citations on your computer. The Send to File selection is available on screens with search results. You can save entire search results or selected citations. If you don't select specific citations before selecting File and clicking on the Send to button, you will create a file on your computer that will contain the entire search results up to a maximum of 10,000 items.

You can also save citations collected from multiple searches by using the Send to Clipboard feature. The Clipboard holds a maximum of 500 items. When you save a file, your browser will prompt you where this file should be placed on your computer, and also give you the opportunity to rename the file.

Saving Entire Search Results:

  1. The default for the Save feature is to save the entire retrieval, up to 10,000 items, unless you specifically select citations. For example, if you use the Send to File on a screen displaying 1-20 items of 30, your saved file will contain all 30 citations.
  2. Use the Display pull-down menu to select a format.
  3. Click Send to File and your items will be saved in this format as plain text.
Saving Selected Citations from a Single Search:
  1. Use the Display pull-down menu to select a format.
  2. Click in the check boxes next to each citation you want to save.
  3. You can move to other pages within the search results to make more selections.
  4. Click Send to File and your selected items will be saved in the Display format as plain text.
Saving Citations from Multiple Searches:
  1. Use the Send to Clipboard selection to add either entire search results or selected items to the Clipboard.
  2. The Clipboard can contain up to 500 items.
  3. After adding citations to the Clipboard, click on the Clipboard link to go to that screen.
  4. Use the Display pull-down menu to select a format.
  5. Choose File and click Send to and your items will be saved in this format as plain text.
Note:
  1. Saving a large retrieval may take several minutes.
  2. To save citations in HTML format, use the Save as... function of your browser. Change the file extension to html. You will only save the citations displayed on the screen so you may wish to use the Show function and Text button to adjust your display as needed.
Print
Use the print function of your Web browser to print all the information and citations displayed on your web page. Before printing, consider using Show to increase the number of documents per page so that the total number of documents is displayed on one page (maximum: 500 per page). You can only print the citations from the displayed page.

Printing Selected Citations:

You may want to print selected items from one or more searches on a single page. You can do this by collecting them in the Clipboard:

  1. Click in the box next to each citation you want and then Send to Clipboard. The Clipboard can hold up to 500 items.
  2. When you are ready to print, click on the Clipboard link to go there.
  3. Within the Clipboard, display the citations in the format and sort order you want to print.
  4. Use your browser's print function to print the page.
Note:
You may also wish to display your citations as Text to strip the sidebar menu and toolbars prior to printing your results.
NCBI Database Links
Links to other resources or NCBI databases are available from the Display pull-down menu. PubMed Central will only process the first 500 items with links. The following links are available: Other Services
Journals Database
The Journals Database is available from the Search pull-down.

The Journals database can be searched using the journal title, the MEDLINE abbreviation, the NLM ID, the ISO (International Organization for Standardization) abbreviation, and the print or electronic ISSNs (International Standard Serial Numbers). The database includes the journals in all Entrez databases.

Note:

  1. Click the journal title from the Summary display or choose Full from the Display pull-down menu to view additional information.
  2. To limit journal searches to PubMed journals, use the "Only PubMed journals" selection in Limits or include the PubMed journal subset (i.e., "journals pubmed [sb]") in your search strategy.
  3. Unqualified journal terms are searched in all journal fields. The following qualifiers are available to limit your search to a specific field: [ISO Abbr] [ISSN] [MEDLINE Abbr] [NLM ID], and [Title].
  4. The Links menu includes links to the Entrez databases in which citations to the journal are found. Select a database under the Links menu to retrieve records for that journal.
  5. Click the NLM ID to display journal information in NLM's online catalog Locatorplus.
  6. If a journal includes parentheses or brackets, e.g., "J Hand Surg [Am]", enter the abbreviation or title without the special characters, j hand surg am.
References
Search Field Descriptions and Tags (in alphabetical order)