ClinVar

NM_005343.3(HRAS):c.34G>T (p.Gly12Cys)

Genes:

HRAS:HRas proto-oncogene, GTPase [Gene - OMIM - HGNC]
LRRC56:leucine rich repeat containing 56 [Gene - HGNC]

Variant type:

single nucleotide variant

Cytogenetic location:

11p15.5

Genomic location:

• Chr11: 534289 (on Assembly GRCh38)
• Chr11: 534289 (on Assembly GRCh37)

Preferred name:

NM_005343.3(HRAS):c.34G>T (p.Gly12Cys)

Other names:

p.G12C:GGC>TGC

HGVS:

• NC_000011.10:g.534289C>A
• NG_007666.1:g.6262G>T
• NM_001318054.1:c.-286G>T
• NM_005343.3:c.34G>T
• NP_005334.1:p.Gly12Cys
• NC_000011.9:g.534289C>A
• NM_005343.2:c.34G>T
• P01112:p.Gly12Cys
• c.34G>T

This HGVS expression did not pass validation

Protein change:

G12C; GLY12CYS

Links:

UniProtKB: P01112#VAR_045975; OMIM: 190020.0014; dbSNP: rs104894229

NCBI 1000 Genomes Browser:

rs104894229

Molecular consequence:

• NM_001318054.1:c.-286G>T - 5 prime UTR variant - [Sequence Ontology: SO:0001623]
• NM_005343.3:c.34G>T - missense variant - [Sequence Ontology: SO:0001583]