Conserved Protein Domain Family
DUF4419
?
pfam14388: DUF4419 (this model, PSSM-Id:405137 is obsolete and has been replaced by 433926)
Domain of unknown function (DUF4419)
This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, eukaryotes and viruses. Proteins in this family are typically between 348 and 454 amino acids in length.
Links
?
Statistics
?
PSSM-Id: 405137
Aligned: 107 rows
Threshold Bit Score: 166.247
Created: 21-May-2020
Updated: 7-Aug-2020
Structure
?
Aligned Rows:
Download Cn3D
Sequence Alignment
?
Format: Row Display: Color Bits: Type Selection: 
CCT70650         59 NGFVLGALKAYSKHHHLILRPDDIWLAILTQLSFFINRNADALRHLFVA-H-NK-KK-------CLSVi---SPEMLk-- 123  Fusarium fu...
Q5UQ60           47 NALIDMIKFAWANHLPVSLRPDDFWIQILTQFATHVNLNSELYQKYFSNkDnPDsET-------QISIgy---------- 109  Acanthamoeb...
jcvi:FSU_0352   110 SAFIDLVALAYARHYAMEISPDDIWLLILDGFRLHVKSNSDSLKDRFVG---PDvDTdikvfanHLTMest--------- 177  Fibrobacter...
jgi:Fisuc_3085  111 pSFINLVALAYAKHYAMEINPDDIWLMILDGFRLHVKNNRKALKDRFVA---PGtDTvvsvmdnSLTLest--------- 178  Fibrobacter...
jcvi:FSU_0348   105 sSFFDVVELAFANHYSLEINPDDIWLMILDGFRYHVKSNREALKDKFVT---PGtDTvvtfednSLTTest--------- 172  Fibrobacter...
Q89ZG9           87 NSFFCGMYQAYADHRPFVLSPDMIWLLINQGFAQHVNANHESLRKYFVN-F-SGkE--------SLIVqshkKLKDPs-- 154  Bacteroides...
WP_008504697     88 HPFFEGMYAAYADHRPFTLSPDMMWLLISQGFANHVNNNSEELRKLFVD-F-DGkT--------SLIVqnnkIKLDDa-- 155  Mucilaginib...
EXX75572         65 NGFIATVLEAYNRHQHLRITPDDVWLTIAQGVSRHINLNEEKYTHLFAQ-N-KRrRS-------QISInasgIFDKErws 135  Rhizophagus...
EFC40647        739 HPVVACYCTAYSEHYPLIVSPDHIWMMITQGLVKHLA-----LRPELIG-NaEEkQN-------KMDIv----------- 794  Naegleria g...
EFC48394        122 HPVVSCYCTAYSEHYPLIIIPDHIWMMISQSLVRHLHLHPEILQQVDIK------KK-------EMRVempthyn----- 183  Naegleria g...

CCT70650        124 ---kQ-------------DMGAMAKV----LAEGMGQNMK-----Dk--SLHKWIIPDFTTTTDTDVVAASVVMAGAFRS 176  Fusarium fu...
Q5UQ60          110 -----------------tDFDNVQDVpiddFVQKILSKLNecierN---DLITKLQCDFTTSNSITLLTSQIAFMYMADK 169  Acanthamoeb...
jcvi:FSU_0352   178 ----------------heEWFGVIAD----FFDNLQEKLPp----EtgaPLRT----KFSTTSPVDYNISRSMVMAIASE 229  Fibrobacter...
jgi:Fisuc_3085  179 ----------------hkEWFYTLSE----LFDSLQAKLPl----EtgaPLRT----KFSTTSPVDANISRTMTMAVASE 230  Fibrobacter...
jcvi:FSU_0348   173 ----------------hhEWFWTLAN----LFEVLQSKLPe----EtglPLKT----KFSTTSPVDYNISSAMVMAVAAE 224  Fibrobacter...
Q89ZG9          155 -----------------lLWEEIFPQ----FTEQIRKEVG-----G---HLVETLTCNFSTTTSLEKTVSEITIMETVKS 205  Bacteroides...
WP_008504697    156 ---kS-------------PWPEVFPE----FSKQIADHTG-----K---QLTDALTADFSTTTPVTKVASQITLMNAVKS 207  Mucilaginib...
EXX75572        136 krivG-------------NWPECVRI----LTEVADKQME-----Ki--DLMKLLECDYSTSTTTSITASRIVLLNPLRE 191  Rhizophagus...
EFC40647        795 ----VampqyidpvsaeiNWEGVVNE----IHQAIVNDVSshkgdErkiKLMDFIDHNFSTSTQVEKVASKMLLMEAFKD 866  Naegleria g...
EFC48394        184 ------------eetqstNWSAVIED----IHQQIVQTCTt----SeklDLDGFLDHNFSTSTSVEKVASKILLMEAFKD 243  Naegleria g...

CCT70650        177 YFNYSF-SYYCGMPSITLLGTKEDWSNLGTRLDGLTTLtnglppdsqpsEELHHFHQLLVPVLNRMARTFDD---PTDPE 252  Fusarium fu...
Q5UQ60          170 FFSYKM-ILGCGIPSIKLDGTIDDWTNLKSKIRTLLEIa---------dDKIKSWLSNLEIITNKIITSIKyp-----gV 234  Acanthamoeb...
jcvi:FSU_0352   230 YYTFFA-YTFCGIPQIRINGTKEDWSLLKDSFNKLATR-----------LDMEWWLQQLNPILDEFVKAFD-----GNS- 291  Fibrobacter...
jgi:Fisuc_3085  231 YYSYRV-TTLCGIPKIKVNGTKEDWTLLKDSFNRLASQ-----------LDMKWWADGLNPILDEFINIYD-----GKI- 292  Fibrobacter...
jcvi:FSU_0348   225 YYEYVV-SSLCGIPKIKINGKKEDWILLKDSFNRLASR-----------LDMDWWAVGLNPILDEFINVFE-----GKI- 286  Fibrobacter...
Q89ZG9          206 YFEFITiMIVCGIPEITLEGTPQDWEKVLNKARGLKEY------------KLEWWISQLEPLLEEFVKASK-----GTI- 267  Bacteroides...
WP_008504697    208 YFDFIViMIGCGIPKITLEGTPQDWRRVLTKTEALRKY------------KLDWWIDEIEPLLKQFILASE-----GKA- 269  Mucilaginib...
EXX75572        192 NSQTNI-DWTCGIPKITLEGKLEDWERIQNKIKTLRKLs----------LDLDFWLDRLEPIIWQLVNTYR-----GDI- 254  Rhizophagus...
EFC40647        867 FYSYKN-DFLCGLPSVTILGTMDDWLGMREKLKLLDEY------------DMAWWRKVLTLILDRIIKTAQEetlTEEL- 932  Naegleria g...
EFC48394        244 YFTYTN-DFMCGIPCVTILGTLQDWTLMRQKVNRLDDF------------GMGWWRKVLALIIDRIIETAQKdtlTDEL- 309  Naegleria g...

CCT70650        253 IVDFWSRMVHEsR--GS----GVHY---ISGWLTAFCFWSS--------------------KGDALYyepqeavdisssd 303  Fusarium fu...
Q5UQ60          235 FVNFWKKMF-YvErcGS----GSQTc--SKGWICHLFLYDK--------------------SYCKLGhvfds-------- 279  Acanthamoeb...
jcvi:FSU_0352   292 SIAFWKNIYKLyEpkGC----GNPK---FNGWFSKFYPYLMgysdkme-------------------------------- 332  Fibrobacter...
jgi:Fisuc_3085  293 NLKHWKNIYKYyEpeGC----GTPD---FSGWISRFFPYTKdlysdte-------------------------------- 333  Fibrobacter...
jcvi:FSU_0348   287 NMDHWRGIYKRyIpeFC----GNVT---FNGWISRFFPYTGldinesnylneridaykrhsPD----------------- 342  Fibrobacter...
Q89ZG9          268 NQEFWRNMFKChSpkSCg---APET---FDGWIIKFFPYDN--------------------EGKRNN------------- 308  Bacteroides...
WP_008504697    270 DRDFWKDMFKYhSegKCg---SPTI---IDGWIVKFFPYNK--------------------DGKRME------------- 310  Mucilaginib...
EXX75572        255 NERFWKRIAh----eFSgtccVPQTtstLSGWITAFLPYDR--------------------------------------- 291  Rhizophagus...
EFC40647        933 -KTFWNGIALFdSs------sGFDF---ISGWINYFFPYDK--------------------ENRVSYhlqkfiemdskfa 982  Naegleria g...
EFC48394        310 -KLFWNGVARFdSs------sGENF---ITGWINYFFPYDK--------------------DGNISNqmqsfmemeerfp 359  Naegleria g...

CCT70650        304 kTr-------------------------------pGCVLDNVR----YHR-TD------TDVIPIGWASAPIDV-D--DN 338  Fusarium fu...
Q5UQ60          280 -----------------------------------------------enelYDlkgitfWDDFPNCEVKCPFMVnSe--- 309  Acanthamoeb...
jcvi:FSU_0352   333 -----------------------------------------fvkrtdWEHdVD------FETLPNALTSVDVKWnYlgQE 365  Fibrobacter...
jgi:Fisuc_3085  334 ----------------------------------------kyikrndWNKkLD------FKQVPRGITFIDIRWeFfqEI 367  Fibrobacter...
jcvi:FSU_0348   343 -----------------------------------------------WNEqLD------VNNVPRGVTSIRIEWnYsgEK 369  Fibrobacter...
Q89ZG9          309 -----------------------------------------------LKQiVG------RKKLPSEIVKVDLKYiEayND 335  Bacteroides...
WP_008504697    311 -----------------------------------------------LKEiAG------TGGLPNEIVKVDLEYqSgdGA 337  Mucilaginib...
EXX75572        292 ------------------------------------------HdkqiVGSlIN------ECDLPDGKIIIPFNVkGg--- 320  Rhizophagus...
EFC40647        983 eNepytddfsqg-------------ylfeetgeseVEKLAKVFr---WREaFE------IGCFPNPITATSVEVlNhqKW 1040 Naegleria g...
EFC48394        360 nVdkyvddfedhgfedcefeeeegenspqssielaALKMQKTFr---WKPsFN------EDCFPCPLAIAKVNVeNhpSL 430  Naegleria g...

CCT70650        339 G--FVYKAMMIAGSMGMKVSSSGEkldrtgrycdtisadsdgrhvvtekgeistvtfkrtdeddletgpDTLQPVIGWWM 416  Fusarium fu...
Q5UQ60          310 ----sRPHYLNAGIYGFTMID------------------------------------------------DHLRlisgftv 337  Acanthamoeb...
jcvi:FSU_0352   366 -----IPLKLYTGFVGIQVDTTS----------------------------------------------KMLKAARGYAL 394  Fibrobacter...
jgi:Fisuc_3085  368 -----IPLKLYTGFIGMQVDTTN----------------------------------------------NMLKASRGYAL 396  Fibrobacter...
jcvi:FSU_0348   370 -----IPLRLYTGFIGIQVDTTT----------------------------------------------NMLKAARGYAL 398  Fibrobacter...
Q89ZG9          336 t-vIETPLELWSGFIGLKQNNEN----------------------------------------------FALRPQIGWMV 368  Bacteroides...
WP_008504697    338 GnfVKTPLELWAGFVGLKQNDRT----------------------------------------------FGLRPEIGWMI 371  Mucilaginib...
EXX75572        321 -----PSLKLVSGFLGVRQDVEENg-------------------------------------------eSVVSPVIGWAV 352  Rhizophagus...
EFC40647       1041 -----KEFHYISGFMGVDYNPEL----------------------------------------------DGIQPVISWAI 1069 Naegleria g...
EFC48394        431 -----KELYYVSGFMGIDFDHEI----------------------------------------------GGLKPVISWAI 459  Naegleria g...
| Disclaimer | Privacy statement | Accessibility |
NCBI Home NCBI Search NCBI SiteMap