5ZHZ,2X7V,2HK0,5B80,1I60,3JU2,9XIM,2ZDS,3NGF,1K77


Conserved Protein Domain Family
AP_endonuc_2
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pfam01261: AP_endonuc_2 (this model, PSSM-Id:396011 is obsolete and has been replaced by 426164)
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Xylose isomerase-like TIM barrel
This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the myo-inositol catabolism pathway, and is required for growth on myo-inositol in Rhizobium leguminosarum bv. viciae.
Links
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Statistics
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PSSM-Id: 396011
Aligned: 166 rows
Threshold Bit Score: 76.2574
Created: 22-May-2020
Updated: 7-Aug-2020
Structure
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Program:
Drawing:
Aligned Rows:
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PubMed ReferencesClick to see Conserved Features Help
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
5ZHZ_A  13 LAAAEAEGADVVQi-FLGNPqswKAPKPRDDA-AALKAAT----LPIYVHAPYLi---nLASANNRVRIPSRKILQETCA 83  Mycobacterium tubercu...
P39305  25 LQLAKTLGFDFVEmsVDETDdrlSRLNWSREQrLALVNAIvetgVRVPSMCLSAhrrfpLGSEDDAVRAQGLEIMRKAIQ 104 Escherichia coli K-12
P37679  23 LVLAKSCGFDFVEmsVDETDerlSRLDWSAAQrTSLVAAMietgVGIPSMCLSAhrrfpFGSRDEAVRERAREIMSKAIR 102 Escherichia coli K-12
P44990  23 LSLAKACGFEFIEmsIDESNdrlSRLNWTKSErIALHQSIiqsgITIPSMCLSAhrrfpFGSKDKKIRQKSFEIMEKAID 102 Haemophilus influenza...
Q7VKM3  23 LSIAKSCGFDFVEmsIDETDerlARLEWSKEQrLALVNSIvttgITIPSMCLSGhrrfpFGTRDQATREKAYEIMEKAIQ 102 [Haemophilus] ducreyi
Q8DN98  22 LNFAKELGFDFVEmsIDERDerlARLDWSKEErLEVVKAIyetgVRIPSICFSGhrrypLGSKDPVLEEKSLELMKKCIE 101 Streptococcus pneumon...
Q8DXN9  22 LQFAKELGFDFVElsIDESDerlARLEWSKEErLELVKAIfetgVRVPTITFSGhrrfpMGSNNPEKEARAMDMMKKCIV 101 Streptococcus agalact...
Q836I1  21 LTWAKKLGFDFLEmsIDESDerlARLAWTPSQlQEFSQLMvkedFFIHSLCLSGhrrfpLGSLNKETREKGRKILSQAIR 100 Enterococcus faecalis
Q7MBX8  27 LSVTKELGFDFLEisVDESDerrSRLDWDDATvYALRHQCerygLPLHSMCLSAhrkfpFGSADAKIREQALLHMEKAIA 106 Vibrio vulnificus YJ016
P75294  42 IAIAKQASFDFIElsIDESDarlQRLDWSDTEiNQLHNELqaqtFCLNSMCLSAhrrfpLGSKNKTTVQQGLTIFEKACV 121 Mycoplasma pneumoniae...

5ZHZ_A  84 AAADIGaAAVIVHGGHVaddNDID--------KGFQRWRKALDRLETE-VPVYLENTaggdhamarRFDTIARLWDVIGD 154 Mycobacterium tubercu...
P39305 105 FAQDVG-IRVIQLAGYD---VYYQeannetrrRFRDGLKESVEMASRAqVTLAMEIMdyp---lmsSISKALGYAHYLNN 177 Escherichia coli K-12
P37679 103 LARDLG-IRTIQLAGYD---VYYEdhdegtrqRFAEGLAWAVEQAAASqVMLAVEIMdta---fmnSISKWKKWDEMLAS 175 Escherichia coli K-12
P44990 103 LSVNLG-IRTIQLAGYD---VYYEkqdeetikYFQEGIEFAVTLAASAqVTLAVEIMdtp---fmsSISRWKKWDTIINS 175 Haemophilus influenza...
Q7VKM3 103 FAVDTG-IRTIQLAGYD---VYYEeqdqgtieRFQQGLAWAVELAASNqVTLAVEIMdtp---fmsSISRWKKWDEMINS 175 [Haemophilus] ducreyi
Q8DN98 102 LAQDLG-VRTIQLAGYD---VYYEekspqtrqRFIKNLRKACDWAEEAqVVLAIEIMddp---finSIEKYLAIEKEIDS 174 Streptococcus pneumon...
Q8DXN9 102 FAQDIG-IRNIQLAGYD---VYYEekspetraRFIKNLRQACTWAEEAqVILSIEIMddp---fmnSIEKYLAVEKEIDS 174 Streptococcus agalact...
Q836I1 101 LAHQLN-IRVIQIAGYD---VFYEektaetreFFLQGLKKGVEEAAQYgVILAVEIMddp---fmnSIQKFLEIKEQIPS 173 Enterococcus faecalis
Q7MBX8 107 LAYKLG-IRTIQLAGYD---VYYEpanrathlRFIEGMKLAAKLAERAgVMLAVEIMdtd---ylnSLSKFEVLNREVNS 179 Vibrio vulnificus YJ016
P75294 122 LARKLG-IRIIQLAAYD---VYYEphdteterNFITNMRKVAELAQKYaVTIAFEVMdtp---fagTIVRCLNLIKRIGK 194 Mycoplasma pneumoniae...

5ZHZ_A 155 TGIGFCLDTCHTWAA-GEAltdavDRIKAITGR--IDLVHCNDSRDEAGSGR--DRHANLGSG-QiDPDLLVAAVKA--- 225 Mycobacterium tubercu...
P39305 178 PWFQLYPDIGNLSAW-DND-----VQMELQAGIghIVAVHVKDTKPGV------FKNVPFGEG-VvDFERCFETLKQsgy 244 Escherichia coli K-12
P37679 176 PWFTVYPDVGNLSAW-GND-----VPAELKLGIdrIAAIHLKDTQPVTGQSPgqFRDVPFGEGcV-DFVGIFKTLHKlny 248 Escherichia coli K-12
P44990 176 PWFTVYPDIGNLSAW-NNN-----IEEELTLGIdkISAIHLKDTYPVTETSKgqFRDVPFGQG-CvDFVHFFSLLKKlny 248 Haemophilus influenza...
Q7VKM3 176 PWFTVYPDIGNLSAW-NDN-----IEQELALGInkISAIHLKDTYKITKDCAgqFRDVPFGDG-CvDFKGFFEILAKlny 248 [Haemophilus] ducreyi
Q8DN98 175 PFLFVYPDIGNVSAW-HND-----IYSEFYLGHhaIAALHLKDTYAVTESSKgqFRDVPFGQG-CvKWEEAFDILKEtny 247 Streptococcus pneumon...
Q8DXN9 175 PYLFVYPDTGNVSAW-HND-----LWSEFYNGHrsIAALHIKDTYAVTETSKgqFRDVPFGQG-CvDWEEMFAVIKKtny 247 Streptococcus agalact...
Q836I1 174 PFLHVYPDLGNLSAWpENN-----PAVELEKGIaeIAAIHLKDTFAVTDTFEgkFREVTFGEG-CvDFTGLLKTLKRlny 247 Enterococcus faecalis
Q7MBX8 180 PYFTAYPDVGNISGW-NYD-----VCTELKLSKphITQIHLKDTHRVTPDSQgqFRDLVIGDG-EvNFDAIFKTLKEt-d 251 Vibrio vulnificus YJ016
P75294 195 ANILLYPDIGNLSQF-STA-----VFDEIALGQdkIVGFHFKDTLPKQ------FKEVPFGTG-TaQFEAALKAIHQy-v 260 Mycoplasma pneumoniae...

5ZHZ_A 226 AGApVICE------------TADQGRKDDIAFLRER 249 Mycobacterium tuberculosis H37Rv
P39305 245 CGP-YLIEmwse-----taeDPAAEVAKARDWVKAR 274 Escherichia coli K-12
P37679 249 RGS-FLIEmwte-----kakEPVLEIIQARRWIEAR 278 Escherichia coli K-12
P44990 249 RGA-FLIEmwte-----kneEPLLEIIQARKWIVQQ 278 Haemophilus influenzae Rd KW20
Q7VKM3 249 RGA-FLIEmwte-----kaeEPIAEIINARRWIEQK 278 [Haemophilus] ducreyi
Q8DN98 248 NGP-FLIEmwsen--cetveETRAAVQEAQAFLYPL 280 Streptococcus pneumoniae R6
Q8DXN9 248 NGP-FLIEmwsen--cetveETRAAIKEAQDFLYPL 280 Streptococcus agalactiae serogroup V
Q836I1 248 SGP-FLIEmwne-----tdlNFQEKIQAAQQYLYPK 277 Enterococcus faecalis
Q7MBX8 252 CVVpLVIEm----------wAQDEDWRAHIHTAQQR 277 Vibrio vulnificus YJ016
P75294 261 PTVpILIEmwskndpaestvQNVAQLKQAKQFYEQQ 296 Mycoplasma pneumoniae M129
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