Conserved Protein Domain Family
MelB

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COG2211: MelB 
Na+/melibiose symporter or related transporter [Carbohydrate transport and metabolism]
Statistics
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PSSM-Id: 441813
Aligned: 640 rows
Threshold Bit Score: 84.1834
Created: 9-Feb-2022
Updated: 17-Oct-2022
Structure
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Aligned Rows:
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection:
WP_015025422  10 D--K-----V--------PI-------------K---QKAAFGAGHL-VLNLLPGALAVF-M-F--FLVTaFG---MD-- 48 
WP_012501185   1 mrlKhfnhyFstdqtatsSIp----------------KILQICLLQL-SHAIAFVLIHSTlN-R--VMIVeFG---IA-- 55 
WP_014431986   1 --mR-----V-----------------------R---AILQLTLVHV-GVSLTVVPITGTlN-R--IMIAdMG---LP-- 38 
WP_012506111   1 ---------M-----------------------Rk-fNLVRLAFFQM-GFGIMLGFLHDTlN-R--VMTSdLG---IS-- 38 
WP_011229501   8 NieRpv--eV--------SI-------------Kn-sQMVRATIASLiGW-----ALDLYdLfLllYVATtIGnlfFPas 58 
WP_015938565  10 StaRa---aVae----pgAApd----------sKa--ATRGIVAATI-GN-----ALEWFdIaIyaLLAIyIGrnfFPss 64 
WP_011378178   5 svpTm---vEsqplppslSLw----------------TMLRLGLFQA-SLGVMSILTLGVlN-R--VMIDeLR---LP-- 56 
WP_015110494   1 ---------MssplrpglTLp----------------ATVRLGLFQG-CLGCLAVIFSGLlN-R--IMLSeLG---FP-- 46 
WP_015941525   1 ---------MamadtllrPVrqvqhwleahprvRmwlRVFRLSLFQF-GMGLSLAPLTGTlN-R--VLINeLG---IA-- 62 
WP_081464620   1 ---------MsspsvlplSLp----------------ATIRLGLLNV-AIGMNALLVFGIlN-R--VMISeWQ---IN-- 46 
WP_015025422  49 PFLAGLLGGLPRI-FDAI-TDPIMGFISDNTKSKLG-RRRPYIFVGA----ILSGILFAL-LFQlse------------- 107
WP_012501185  56 AWIVGAVMGFHNL--LAF-VRPMIGLFSDTH-AFLGyRRTPIIILGN----LLVAAGVIGsI-Ygai------------- 113
WP_014431986  39 AVLVGLLVALPYM-LSPL--QVFVGNWADR-RPLWGmHRSPWILLGG----LMASCGSYM-AAHaaf------------- 96 
WP_012506111  39 STIVFGLISLKEL-LAVFgVKVWAGNISDRTH-ILGyKRTPFILLGL----VTCVISFML-APSaayevtiagvgfaemi 111
WP_011229501  59 NQTLSLAAVYASFaVTLL-MRPLGSAIFGVYADKNG-RKK-AMTVAI----IGAGLSTTA-FGLlpt------------- 117
WP_015938565  65 DPGVELIQAFAVFgVSYL-IRPLGGLVLGSFADRHG-LKK-GLTVTI----RLMVLGTAL-LAFmpn------------- 123
WP_011378178  57 ALLVAGAIAMHQFvA--P-VRVWFGQLSDTR-PLWGlHRSGYIWLGSatfcLVASLAVRL-VWPlaa------------- 118
WP_015110494  47 GLLVGGALAFEQFvA--P-SRVLFGQISDAH-PLASrHRVPYVLLGTaafcLMAVLSVPL-IFRvgr------------- 108
WP_015941525  63 AFLVGSLLALHYFiS--P-ARAIFGYRSDIHRAAGRw-RTPYLVLGA----MLTYGGLAT-APFsli------------- 120
WP_081464620  47 AALVGIFVCAHYVvC--P-MRTLAGYASDTR-PLWGyRRTPYIVGGM----LVALGSLLL-ILHaaq------------- 104
WP_015025422 108 --dnsVTF------NFCYFLLM-----SLVFLVG--N--TMFATPLVGLGYEMTP-D-YNERTRLMAFA-NTIGQIAWMI 167
WP_012501185 114 --wmsHAFy----pGLALTLFA-----SLIYGIG--I--NVAGTMFYALLTDNAG---ENYKSIAVSLG-WIVLISGSIL 174
WP_014431986  97 --ameENFa----lGLLAAFVV-----FLIWGIG--V--NIASVSYLSLTSELTErSpKTWRTAAVGVM-WTAMILSTIV 160
WP_012506111 112 pammtDi-------GLLkLVVI-----FLAFGFG--L--QVATTAYYALIADYVG-D--KHIGKVTSAS-WTFMVLTTIV 171
WP_011229501 118 ---ihQVG--------VAASIA-----FLILRLVqgIfvGGVVASTHTIGTESAS---PKYRGLMSGLIgGGGAGLGALF 178
WP_015938565 124 ---ygTIG--------ILAPIG-----IVLARLIqgFsaGGEFGAATAYLIAQNG----KRKGFLGSFQ-FASQGLGSLI 182
WP_011378178 119 --sfeQSGw----gGNTWLYAIalgltFALYGVA--I--SASSTPFAALLVDVTDeR---TRPKLVSIV-WSMLMVGIVI 184
WP_015110494 109 --lleDGSq----pGLAFGIAAlc-glFALYGLA--V--SLATTPYLALVIDRTSeQ---ERPRAVSII-WCMLTVGIVI 173
WP_015941525 121 --llsGEGflpfpfAVIVCFAI-----FFAYGLG--V--NIAETIYLAIVSDVTPpQ---ERGRVLSVL-WVALVLGTIV 185
WP_081464620 105 --wmrTQPf----wGSLACGMA-----FALWGLG--L--NAASVPYLALMSDLSGp----HRARTISVA-WFMMVAFGIV 164
WP_015025422 168 VP-WFWVVIadP-TVfplsdvalrtigemgltgdelqkitnekL----Q------ANGVRQLSLMVGLVCA-VLGILPAL 234
WP_012501185 175 AS-AVAGYYl-D-EFs---------------------------------------eSQLISLFWVGAIASM-LITWMAVL 211
WP_014431986 161 AS-IALSRVl-Ql------------------------------Da---------sPSGVITAFGAVWLVAT-LFVVVGAA 198
WP_012506111 172 SA-RIVGGYl-D-VYt---------------------------------------PERLVNVAFIGGLVALgIA-LFAFV 208
WP_011229501 179 AS-IAYSIVs-A-IFp--------------------------gDaf--------dTlGWRIMFFTGIIGAL-FG-LFIFR 219
WP_015938565 183 AA-IFVAVLt-T-VLt--------------------------dAqm--------tEwGWRIPFLFGLLVGP-AG-FLIRR 223
WP_011378178 185 GG-ITTGILl-K-SVga-------------------------eSslp------eiQGSLQQLFTVVPLLVF-GTILLATV 229
WP_015110494 174 GA-VAIGVSl-R-SLdg-------------------------vNdpv------vlEATLSQFMASVAGVVM-LLTVVATW 218
WP_015941525 186 GS-LLIGELl-L-DYs---------------------------------------HTRLIQVMQGSALAFV-FLTFMSML 222
WP_081464620 165 ATgIVIAKYf-DlNLsk-------------------------lStditAldtaalDQVLQQLFYTVVGISA-LLMLAAVI 217
WP_015025422 235 FCKG-MDA-G---QmenrkkismgtlsSS-F----K--ELFQGIVQVSK-C--KPFIKLCSATFLVFNGFQMVASFSFFI 299
WP_012501185 212 Gs-EkRNDlP---Sap----------nDTtHp--kL--ELRSSLKKLAA-N--QPVYRFFSFMFVTVIAIQGQDVILEPF 270
WP_014431986 199 Gi-EpSRT-----Eshv--------vrHTaNn------P-LEALQVLAH-N--ATARRFFIYLLLVLIGVRAQDVLLEPY 254
WP_012506111 209 GVEE-RNS-----Seskk-----ghgaES------L--SFGQSIKLLTS-S--PKTMLFAFYIFVSIFALFSNEIVMEPF 266
WP_011229501 220 SLDE-S---PlwkQlke--------kqSKdKmveqQksP----FKMFLT-KyyKVLFVNLMIVIGGGSGYYLTAGFIPTF 282
WP_015938565 224 EMKE-V---Pv--Qrg---------aaEE-Kh---S--P----IRDVFAtQ--KTGMLLAGGALAVSTALNFILQYMPTF 276
WP_011378178 230 Gv-ErRYS-----Gfaers---qsrdrEDs-------iTLGRALRVLTA-S--RQTGFFFGFLAVLTFSLFLQEAILEPY 290
WP_015110494 219 Gm-EsPLR-----Ertdgt----avrrEDa-------iGLRQSWTLITS-S--RQVLIFFSFLILFTLALFLQDPVLESY 278
WP_015941525 223 Dq-ErLKP-----Ngel-------vdfTPvRv---Re-TLGESLRMLAA-Q--RPLRNLFIVLALATTGFAVHDVLLEPY 282
WP_081464620 218 Gm-EpRHR-----Nlaa--------edEKp-------pTLRETIAVMTA-D--RDSKIFFAVVALGIFGVNAQDVLLEPY 273
WP_015025422 300 IVFYIynGDyGQaGTWpAW-FA-SITALVTaFLVIPI-IS-SIANKFGKRKAFLISTAISIVGYGLKW--WgFD-NSlna 372
WP_012501185 271 GAHIF--GM-NI-AET-TK-LT-QVWGAGT-IFGIVV-LGlFFVNRIGKKRTTYLGCTLSAIGFLIIS--A-SAw----- 333
WP_014431986 255 AADAL--GM-SV-SET-TR-LE-ALWGVGV-FITLLGgMG--LVRLFGKRLNIYVGGLVAIVAFGLVI--L-AGaVG--- 318
WP_012506111 267 GADVF--GM-PV-GVT-TK-LFrPTMGGMQ-LIFMLL-VG-FLLNRIGKKRGALIGNLFCIMGFSIII--V-SGffQ--- 331
WP_011229501 283 LKVVN--KV-PA-AVS-SG-VL-IATSITT-ILAAIV-VG-HLSELIGRKKTFMIIGILCVFG-LPYFy-L-Sl-AH--- 345
WP_015938565 277 AIKEL--GL-EP-GI--SFtSL-IITGVIL-TFGTPL-VG-HLSDKYGRLNIMVPTVVVLLIAVVPLFmwV-IN-AK--- 341
WP_011378178 291 AGQVF--GF-SV-GQS-SQ-LN-AYWGFGT-LIGTAV-TGfLVVPKLGKERTAQVGCGLSALCFCLII--A-AGwGP--- 355
WP_015110494 279 GAQVF--AM-PI-AAT-AQ-LN-AFWGVGT-LVGLLV-AGlWVVPRLGKMATARLGCQLIALSLLLLL--V-AGlTA--- 343
WP_015941525 283 GGQVL--GM-TV-AET-TR-LT-AVWGGGM-LTAIVL-TGwLLWRGHSALRLLGSSTLLGILGFATIS--L-STtPD--- 347
WP_081464620 274 GAQVL--QM-SL-ADT-TR-LQ-PTWGGAT-LISMLF-AGfILARRLSRKQIALLGAFLSTLGLGLVI--A-AAgLG--- 338
WP_015025422 373 qfnassagqglnnfvasifnainpfldsigmswfsidisqgAPWLMFVPIP-F-MAFGLGGLFTLMMSMTADVCDLDEle 450
WP_012501185 334 ----------------------------------------fDVTVFKSGVF-L-LGLGNGALTVGSLTMMMDMTTKAN-- 369
WP_014431986 319 -----------------------------------------NVPFFLVSVF-L-LGLASGLMTVSNLSFMLDMTIPQS-- 353
WP_012506111 332 -----------------------------------------DETILRAGLI-V-TGIGLGASSVSNITMMMTMT------ 362
WP_011229501 346 -----------------------------------------STTTTSIYLNaIgLVFLGNASYAPVLIFLNERFPTEV-- 382
WP_015938565 342 -----------------------------------------SFLVLALVMT-I-LGLLKASYFGALPSVMSDSFDVRT-- 376
WP_011378178 356 -----------------------------------------WPSLLRSAIV-L-FGLGAGIATSGSIILMLDFTLAET-- 390
WP_015110494 344 -----------------------------------------RIPFLQAVMV-L-FGLAAGIGTNSALCLMLDLTLPQA-- 378
WP_015941525 348 -----------------------------------------HVGQFLGGIA-L-IGMGRGMLIVGGLSLVMGLCDRAH-- 382
WP_081464620 339 ------------------------------------------SGVLRVGVF-T-LGMGSGIFAVGALSMMMDMTRPGQ-- 372
WP_015025422 451 NGLpRKEGTFGAIYWWMVKVGQAIALVL----GGAIL-TLVGFD--EGAvtQt-V-E-TMN--------QLRIADI-ILP 511
WP_012501185 370 ------TGLFMGLWGLAQAIPNFLANAV----GGAIR-DISLFF----T--Q----Nqy---------vGYTTAF--AIE 417
WP_014431986 354 ------VGLYMGAWGVANFVAQSLGNV-----GGALLrDIAYWV--SG--------NvVL---------GYMTVF--GIE 401
WP_012506111 363 AGR---SGVYIGLWGTAQSLAMFIGHFg----AGVIR-DVVHAL--SN--------Sym---------wAYTAIF--GLE 413
WP_011229501 383 ----RSTGTGLS-----WNVGFAIGGMMpt-fVNL----ASGTV-------EhiPyT-LMY-------------FT---- 423
WP_015938565 377 ----RATGLSFS-----YNTAVVAFGGFtpmiAAFLV-QQTGQAvaPGy-------------------------YL---- 417
WP_011378178 391 ------AGTFIGAWGLAQALSRAVATVS----GGAIF-DLgKLG--LS--------AeALAaggaalfpAYALVF--AVQ 447
WP_015110494 379 ------AGTFVGVWGLAQALSRAIGKLL----GGglydigralplgdgpygpfalvlgvellvalaallllgyvnvrqfr 448
WP_015941525 383 ------AGLFIALWGITQALAQGIGTIS----AGLAR-DViGRM--SG--------VvAN---------GYIAVYLsALT 432
WP_081464620 373 ------AATYLGVWGIAQALAQGTAGLT----AGVGR-AGlEAV--TG--------QiGL---------AYQGVF--ALE 420
WP_015025422 512 VSTAALAFIVMW------KYDL---D-EKRVR---GIgaE-LKIrnS 544
WP_012501185 418 IIGLFIAILILR------TVDVa--EfKKNSA---QLfyEsISN--S 451
WP_014431986 402 IIGVALSLLLFRt------iTVe--QfQHDAQl--ELv-DvLAA--S 435
WP_012506111 414 IIAFAAASLLLP--------KIskdDfEEESKi--KIa-EvLAA--S 447
WP_011229501 424 IVIYLVYILGSFii-------------pET-Kg--NL--K------- 445
WP_015938565 418 GVVAIISLVALAt-----GVKL-----Rg------------IR---- 438
WP_011378178 448 ALGMLVAIACLSr------vNVq--EfRQDSRv--RLs-DvLAA--E 481
WP_015110494 449 edtshslsqvlememg------------------------------- 464
WP_015941525 433 LIAVAGAMLLILsw--rgQLRAe--QvRSPWSs-----lDqVNA--D 468
WP_081464620 421 ALALMATVWLLLsmgrttPQKLe--ErRDDRHgieHLa-DvVSA--N 462
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