Conserved Protein Domain Family
Bbox1_BBX-like
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cd19821: Bbox1_BBX-like 
B-box-type 1 zinc finger found in B-box (BBX) family of plant transcription factors and similar proteins
The BBX family includes a group of zinc finger transcription factors that contain one or two B-box motifs, and sometimes also feature a CCT (CONSTANS, CO-like, and TOC1) domain. They play important roles in plant growth and development, including seedling photomorphogenesis, photoperiodic regulation of flowering, shade avoidance, and responses to biotic and abiotic stresses. Their B-box motifs show high sequence similarity with B-Box-type 1 zinc finger found in tripartite motif-containing proteins (TRIMs) and are involved in mediating transcriptional regulation and protein-protein interaction in plant signaling. The type 1 B-box (Bbox1) zinc finger is characterized by a C6H2 zinc-binding consensus motif; this family contains a modified motif, C3XC2H2, where X can be D, E, C or H.
Links
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Statistics
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PSSM-Id: 380879
Aligned: 52 rows
Threshold Bit Score: 48.8331
Created: 6-Sep-2018
Updated: 2-Oct-2020
Structure
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Aligned Rows:
Download Cn3D
 
Zn binding site
Feature 1: Zn binding site [ion binding site], 8 residue positions
Conserved feature residue pattern:C C C [CEDH] C C H HClick to see conserved feature residue pattern help
Evidence:
  • Comment:Based on the structure evidence that Homo sapiens Midline-1 (2JUN) binds two Zn2+ ions through its B-box motif.
Scroll to Sequence Alignment Display
Sequence Alignment
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Format: Row Display: Color Bits: Type Selection: 
Feature 1         #  #          #  #    #  #    #                 #     
O50055        11 ACDtCRSa--aCTVYCRaDSAYLCSSCDAqVHAAnrl---------asrHERVRV 54  thale cress
NP_597141    192 ICDrCRMn--qSVSFCPaERASFCAECDEeVHSDhfl----------krHVRYYF 234 Encephalitozoon cuniculi GB-M1
XP_013163595 155 ICErCKSk--qSISFCPsERANFCEECDEaVHIDefh----------krHDRYYF 197 Asian swallowtail
C0SVM5         4 LCDaCENa--aAIIFCAaDEAALCRPCDEkVHMCnkl---------asrHVRVGL 47  thale cress
Q9SJU5         4 LCDaCESa--aAIVFCAaDEAALCCSCDEkVHKCnkl---------asrHLRVGL 47  thale cress
Q9LUA9        47 VCErCNAq--pASVRCSdERVSLCQNCDWsGHDGknst--------ttsHHKRQT 91  thale cress
Q9SSE5        47 VCErCNAq--pATVRCVeERVSLCQNCDWsGHNNsnnnnssssstspqqHKRQTI 99  thale cress
XP_010419061   8 LCDsCKDq--pCVVRCFdHRMFLCHGCNDkFHVGggv---------sseHHRRDD 51  false flax
EFO65547      62 ACEnCSSsvspSGMYCLaCDLLLCQACDRtVHAPpal----------skHDRRPF 106 Giardia lamblia P15
PNR35891      47 LCHsCNVr--pAAVRCPsCHSSLCETCDDeIHNPilg---------tdqHQRRSF 90  Physcomitrella patens

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