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Development of the human eye. (A) The retina develops as an outpocketing from the neural tube, called the optic vesicle. (B) The optic vesicle invaginates to form the optic cup. (C, D) The inner wall of the optic cup becomes the neural retina, while the outer wall becomes the pigment epithelium. (A-C from Hilfer and Yang, 1980; D courtesy of K. Tosney.)