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Table 16-2

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   Drugs That Affect Actin Filaments and Microtubules

ACTIN-SPECIFIC DRUGS
Phalloidinbinds and stabilizes filaments
Cytochalasincaps filament plus ends
Swinholidesevers filaments
Latrunculinbinds subunits and prevents their polymerization
MICROTUBULE-SPECIFIC DRUGS
Taxolbinds and stabilizes microtubules
Colchicine, colcemidbinds subunits and prevents their polymerization
Vinblastine, vincristinebinds subunits and prevents their polymerization
Nocodazolebinds subunits and prevents their polymerization