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Maturation from early to late endosomes occurs through the formation of multivesicular bodies, which contain large amounts of invaginated membrane and internal vesicles (hence their name). These bodies move inward along microtubules, and recycling of components to the plasma membrane continues as the bodies move. The multivesicular bodies gradually turn into late endosomes, either by fusing with each other or by fusing with preexisting late endosomes. The late endosomes no longer send vesicles to the plasma membrane but communicate with the trans Golgi network via transport vesicles, which deliver the proteins that will convert the late endosome into a lysosome.
