NCBI » Bookshelf » Molecular Biology of the Cell » Internal Organization of the Cell » Membrane Structure

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Figure 10-24

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   Solubilizing membrane proteins with a mild detergent

The detergent disrupts the lipid bilayer and brings the proteins into solution as protein-lipid-detergent complexes. The phospholipids in the membrane are also solubilized by the detergent.

Copyright © 2002 Bruce Alberts, Dennis Bray, Julian Lewis, Martin Raff, Keith Roberts, and James D. Watson