-- NIH Consensus Development Program — State of the Science Statements -- NCBI Bookshelf

About these Reports
21 Management of the Clinically Inapparent Adrenal Mass (Incidentaloma): State-of-the-Science Statement, February 4-6, 2002National Institutes of Health
- Introduction
- 1. What are the causes, prevalence, and natural history of clinically inapparent adrenal masses?
- 2. Based on available scientific evidence, what is the appropriate evaluation of a clinically inapparent adrenal mass?
- 3. What criteria should guide the decision on surgical versus nonsurgical management of these masses?
- 4. If surgery is needed, what is the appropriate procedure?
- 5. What is the appropriate followup for patients for each management approach?
- 6. What additional research is needed to guide practice?
- Conclusions
- State-of-the-Science Panel
- Speakers
- Planning Committee
- Conference Sponsors
- Conference Cosponsors
20 Endoscopic Retrograde Cholangiopancreatography (ERCP) for Diagnosis and Therapy: State-of-the-Science Statement, January 16, 2002 4:15 PM [Draft Statement]National Institutes of Health
- Introduction
- 1. What is the role of ERCP in gallstone disease?
- 2. What is the role of ERCP in pancreatic and biliary malignancy?
- 3. What is the role of ERCP in pancreatitis?
- 4. What is the role of ERCP in abdominal pain of possible pancreatic or biliary origin?
- 5. What are the factors determining adverse events or success?
- 6. What are promising new research directions for the prevention, diagnosis, and treatment of dental caries?
- State-of-the-Science Panel
- Speakers
- Planning Committee
- Conference Sponsors
- Conference Cosponsors
19 Improving Medical Implant Performance Through Retrieval Information: Challenges and Opportunities: NIH Technology Assessment Conference Summary, January 10-12, 2000National Institutes of Health
- Abstract
- Introduction
- 1. What are the patient, health care provider, and societal expectations of the lifetime costs, risks, and benefits of medical implants?
- 2. What are the legal, ethical, religious, cultural, public policy, and economic barriers to implant retrieval and reporting, and how can they be overcome?
- 3. What information is necessary to evaluate and improve implant and material performance and device design?
- 4. What can the role of information data systems be in educating the public, medical community, and policymakers about medical implants and retrieval?
- 5. What future research and institutional support is necessary to ensure continuing advances in implantable devices?
- Conclusions
- Recommendations
- Technology Assessment Panel
- Speakers
- Planning Committee
- Conference Sponsors
- Conference Co-sponsors
18 Management of Temporomandibular Disorders: Technology Assessment Conference Statement, April 29-May 1, 1996National Institutes of Health
- Abstract
- Introduction
- 1. What Clinical Conditions Are Classified as Temporomandibular Disorders, and What Occurs if These Conditions Are Left Untreated?
- 2. What Types of Symptoms, Signs, and Other Assessments Provide a Basis for Initiating Therapeutic Interventions?
- 3. What Are Effective Approaches to the Initial Management and Treatment of Patients With Various TMD Subtypes?
- 4. What Are Effective Approaches to Management and Treatment of Patients With Persistent TMD Pain and Dysfunction?
- 5. What Are the Most Productive Directions for Future Research, and What Types of New Collaborations and Partnerships Should Be Developed for Pursuing These Directions?
- Conclusions
- Technology Assessment Panel
- Speakers
- Planning Committee
- Conference Sponsors
- Conference Cosponsors
- Statement Availability
- Bibliography
17 Integration of Behavioral and Relaxation Approaches into the Treatment of Chronic Pain and Insomnia: Technology Assessment Conference Statement, October 16-18, 1995National Institutes of Health
- Abstract
- Introduction
- What Behavioral and Relaxation Approaches Are Used for Conditions Such as Chronic Pain and Insomnia?
- How Successful Are These Approaches?
- How Do These Approaches Work?
- Are There Barriers to the Appropriate Integration of These Approaches Into Health Care?
- What Are the Significant Issues for Future Research and Applications?
- Technology Assessment Panel
- Speakers
- Planning Committee
- Conference Sponsors
- Conference Cosponsors
- About the NIH Consensus Development Program
- Statement Availability
- Bibliography
16 Gaucher Disease: Current Issues in Diagnosis and Treatment [** Draft **]: Technology Assessment Conference Statement, February 27-March 1, 1995National Institutes of Health
- Introduction
- What Is the Natural History of Gaucher Disease, and What Is the Appropriate Technology to Assess the Severity and to Predict the Progression of This Disorder?
- What Are the Roles of Current Molecular and Enzymatic Assays for Ascertaining Affected Individuals and Carriers in Various Populations?
- What Are the Indications for Treatment of Patients With Gaucher Disease, and What Are the Appropriate Modes of Therapy?
- What Are the Goals for and Consequences of Treatment, and How Can the Therapeutic Interventions Be Assessed?
- Under What Circumstances Could Genotype/Phenotype Correlations Be Used for Patient Care and Counseling?
- What Are Appropriate Directions for Future Research and Other Relevant Issues That Should Be Pursued?
- Conclusions
- Consensus Development Panel
- Speakers
- Planning Committee
- Conference Sponsors
- Conference Cosponsors
- About the NIH Technology Assessment Program
15 Bioelectrical Impedance Analysis in Body Composition Measurement [** Draft **]: Technology Assessment Conference Statement, December 12-14, 1994National Institutes of Health
- Introduction
- 1. What Does BIA Measure in Terms of Electrical and Biological Parameters, and How Safe Is It?
- 2. How Should BIA Be Performed, and How Can BIA Measurements Be Standardized?
- 3. How Valid Is the BIA Technology in the Estimation of Total Body Water, Fat-Free Mass, and Adiposity?
- 4. What Are the Appropriate Clinical Uses of BIA Technology, and What Are the Limitations?
- 5. What Are the Future Directions for Basic Science, Clinical Research, and Epidemiological Evaluation of Body Composition Measurements?
- Conclusions
- [Contributors]
- About the NIH Technology Assessment Program
14 The Persian Gulf Experience and Health: Technology Assessment Workshop Statement, April 27-29, 1994National Institutes of Health
- Introduction
- What Is The Evidence for an Increased Incidence of Unexpected Illnesses Attributable to Service in the Persian Gulf War?
- If Unexpected Illnesses Have Occurred, What Are The Components of The Most Practical Working Case Definition(s) Based on Existing Data?
- If Unexpected Illnesses Have Occurred, What Are the Plausible Etiologies and Biological Explanations for These Unexpected Illnesses?
- What Future Research Is Necessary?
- Conclusions
- Workshop Panel
- Speakers
- Veterans Organizations
- Planning Committee
- Workshop Sponsors
- About the NIH Technology Assessment Program
13 An Evidence Based Health Care System: The Case for Clinical Trials Registries
- Creating an NIH Clinical Trials Registry: A User Friendly Approach to Health Care
- The Case for Clinical Trials Registries
- Ongoing Trials a Greater Challenge Than Those Already Published
12 Ultrasound Screening: Implications of the RADIUS Study [Draft Summary]: NIH Technology Assessment Workshop, Rockville, MD,December 3, 1993
- Draft Report
- Speakers
- About the NIH Technology Assessment Program
11 The Head and Heart of Chaos: Nonlinear Dynamics in Biological Systems: Office of Medical Applications of Research Workshop, June 15-16, 1992National Institutes of Health
- Preface
- Introduction to the Head and Heart of Chaos Nonlinear Dynamics in Biological Systems
- Report on the Workshop
- Principal Issues Arising from the Workshop
- Conclusion
- Critical Panel
- Speakers and Discussants
- Planning Committee
- About the NIH Technology Assessment Program
10 Methods for Voluntary Weight Loss and Control: Technology,Assessment Conference Statement, March 30 - April 1, 1992National Institutes of Health, Office of Medical Applications of Research
- Introduction
- How Often and in What Ways Do Americans Try to Lose Weight?
- How Successful Are Various Methods for Weight Loss and Control? What Are the Attributes of and Barriers to Successful Weight Loss Methods/Approaches?
- What Are the Short- and Long-Term Benefits and Adverse Effects of Weight Loss?
- What Are the Fundamental Principles That Should Be Used to Select a Personal Weight Loss and Control Strategy?
- What Should Be the Future Directions for Research on Weight Loss and Control?
- Conclusions
- Technology Assessment Panel
- Speakers
- Planning Committee
- Liaison Committee Members
- Conference Sponsors
- About the NIH Technology Assessment Program
9 Effects and Side Effects of Dental Restorative Materials: Technology Assessment Conference Statement, August 26-28, 1991National Institutes of Health, Office of Medical Applications of Research
- Introduction
- What Are the Needs and Benefits of Tooth Restorations?
- What Are the Incidence and Severity of Side Effects Associated with Tooth Restorative Materials?
- Do Materials for Tooth Restorations Contribute to Systemic Disease and Reactions?
- What Are the Benefit/Risk Ratios of Different Tooth Restorative Materials?
- What Should Be the Future Directions for Research on Materials for Tooth Restorations?
- Conclusions and Recommendations
- Technology Assessment Panel
- Speakers
- Planning Committee
- Conference Sponsors
- About the NIH Technology Assessment Program
8 Clinical Trials Results: Exploring the Dissemination Process: Technology Assessment Workshop, January 15,1991National Institutes of Health, Office of Medical Applications of Research
- Issuing Clinical Alerts
- When to Do a Clinical Alert
- Ensuring Journal Publication
- Notifying Physicians and Press
- About the NIH Technology Assessment Program
7 Bovine Somatotropin: Technology Assessment Conference Statement, December 5-7, 1990National Institutes of Health, Office of Medical Applications of Research
- Introduction
- What Is the Role of Milk in Human Nutrition, and How Is Its Safety for Human Consumption Monitored?
- What Is the Comparative Biology of Human and Bovine Lactation and Milk Composition?
- What is the Effect of Administration Of rBST on Milk Production of Cows and on the Nutritional Quality and Hormonal Content of Their Meat and Milk?
- What are the Health Effects on Cows Resulting from Administration of rBST?
- What are the Health Effects on Humans Resulting from Consumption of Meat or Milk from Cows Given rBST?
- What Further Animal and Human Research is Needed on the Effects and Use of rBST?
- Conclusions and Recommendations
- Technology Assessment Panel
- Speakers
- Planning Committee
- Conference Sponsors
- About the NIH Technology Assessment Program
6 Report on the Workshop on Diffusion of ECMO Technology: Technology Assessment Conference Statement, December 5-7, 1990National Institutes of Health, Office of Medical Applications of Research
- Introduction
- Current State of Knowledge Concerning Populations to Benefit and Indications for Use
- Prevention and Therapeutic Alternatives
- Research
- Policy Considerations Influencing the Diffusion of ECMO
- Diffusion of Medical Technology: The Case of ECMO
- Extracorporeal Life Support: State-of-the-Art 1990
- Neurological Outcome after Extracorporeal Membrane Oxygenation Therapy in the Newborn
- Extracorporeal Membrane Oxygenation Versus Conventional Medical Therapy for Management of Persistent Pulmonary Hypertension of the Neonate: A Decision Analysis
- Extracorporeal Membrane Oxygenation: Cost, Organization, and Policy Considerations
- Planning Committee
- Invited Participants
- About the NIH Technology Assessment Program
5 Health Care Delivery Research Using Hospital Firms: Workshop Summary, April 30 - May 1, 1990National Institutes of Health, Office of Medical Applications of Research
- Executive Summary
- The Basic Concept
- What Are Firms?
- Examples of Firm Systems
- Examples of Research
- Methodological Issues
- Ethics of Firms Research
- Efficiency in Research
- Management Information Systems
- Clinical Guidelines Trials
- The Future: Multicenter Trials
- Conclusion
- Speakers
- About the NIH Technology Assessment Program
- Bibliography
4 Modeling in Biomedical Research: An Assessment of Current and Potential Approaches: Applications to Studies in Cardiovascular/Pulmonary Function and Diabetes: Technology Assessment May 1-3, 1989National Institutes of Health, Office of Medical Applications of Research
- Introduction
- Summary of Conclusions
- Specific Cases
- Summary and Recommendations
- Technology Assessment Panel
- Speakers
- Planning Committee
- Conference Sponsors
- About the NIH Technology Assessment Program
3 The Health Benefits of Pets: Workshop, September 10-11, 1987National Institutes of Health, Office of Medical Applications of Research
- Overview
- The Role of Pets in Cardiovascular Health
- The Role of Pets in Child Development
- Health Correlates of Pets in Older Persons
- The Role of Pets in Social and Therapeutic Effects
- Safety and Risks in People-Pet Relationships
- Future Research Directions
- Technology Assessment Panel
- Speakers
- Planning Committee
- Conference Sponsors
- About the NIH Technology Assessment Program
2 Donor Registries for Bone Marrow Transplantation: Technology Assessment, May 13-15, 1985National Institutes of Health, Office of Medical Applications of Research
- Introduction
- What Is the Experience with the Possible Alternatives to HLA-Identical Siblings as Bone Marrow Donors for Transplantation? Are These Alternatives Comparable?
- Should a National Bone Marrow Donor Registry Be Established?
- To What Extent Could the Existing Registries/Blood Donor Programs Be Utilized as a Source of Potential Unrelated Bone Marrow Donors? What Would Be the Impact on These Programs?
- What Are the Logistical, Legal, and Ethical Issues Involved in Establishing Registries of Unrelated Donors? to What Risks Are Donors Exposed?
- Recommendations Involving Donors
- Other Issues
- Recommendations Involving Recipients
- Research and Evaluation
- Conclusion
- Technology Assessment Panel
- Speakers
- Planning Committee
- Conference Sponsors
- About the NIH Technology Assessment Program
1 Evaluating the Elderly Patient: The Case for Assessment Technology: NIH Technology Assessment Conference Summary, June 29-30, 1983National Institutes of Health
- Foreword
- Assessment as a Useful Tool
- The Experience with Employment of Assessment Instruments
- The Science Base of Assessment Technology
- Afterword (Dr. Isadore Rossman)
- About the NIH Technology Assessment Program

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