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Prepared by:
Tracy Wolff, MD, MPH
Catherine Takacs Witkop, MD MPH
Therese Miller, DrPH
Shamsuzzoha B. Syed, MD, MPH, DPH (Cantab)
Agency for Healthcare Research and Quality
U.S. Department of Health and Human Services
540 Gaither Road
Rockville, MD 20850
AHRQ Publication No. 09-05132-EF-1
May 2009
This report is based on research conducted by staff of the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. The investigators involved have declared no conflicts of interest with objectively conducting this research. The findings and conclusions in this document are those of the authors, who are responsible for its content, and do not necessarily represent the views of AHRQ. No statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services.
The information in this report is intended to help clinicians, employers, policymakers, and others make informed decisions about the provision of health care services. This report is intended as a reference and not as a substitute for clinical judgment.
This report may be used, in whole or in part, as the basis for the development of clinical practice guidelines and other quality enhancement tools, or as a basis for reimbursement and coverage policies. AHRQ or U.S. Department of Health and Human Services endorsement of such derivative products may not be stated or implied.
Suggested Citation: Wolff T, Witkop CT, Miller T. Syed SB. Folic Acid Supplementation for the Prevention of Neural Tube Defects: An Update of the Evidence for the U.S. Preventive Services Task Force. Evidence Synthesis No. 70. AHRQ Publication No. 09-051132-EF-1. Rockville, Maryland: Agency for Healthcare Research and Quality. May 2009.
Prepared by:
Tracy Wolff, MD, MPH
Catherine Takacs Witkop, MD MPH
Therese Miller, DrPH
Shamsuzzoha B. Syed, MD, MPH, DPH (Cantab)
Agency for Healthcare Research and Quality
U.S. Department of Health and Human Services
540 Gaither Road
Rockville, MD 20850
AHRQ Publication No. 09-05132-EF-1
May 2009
This report is based on research conducted by staff of the Agency for Healthcare Research and Quality (AHRQ), Rockville, MD. The investigators involved have declared no conflicts of interest with objectively conducting this research. The findings and conclusions in this document are those of the authors, who are responsible for its content, and do not necessarily represent the views of AHRQ. No statement in this report should be construed as an official position of AHRQ or of the U.S. Department of Health and Human Services.
The information in this report is intended to help clinicians, employers, policymakers, and others make informed decisions about the provision of health care services. This report is intended as a reference and not as a substitute for clinical judgment.
This report may be used, in whole or in part, as the basis for the development of clinical practice guidelines and other quality enhancement tools, or as a basis for reimbursement and coverage policies. AHRQ or U.S. Department of Health and Human Services endorsement of such derivative products may not be stated or implied.
Suggested Citation: Wolff T, Witkop CT, Miller T. Syed SB. Folic Acid Supplementation for the Prevention of Neural Tube Defects: An Update of the Evidence for the U.S. Preventive Services Task Force. Evidence Synthesis No. 70. AHRQ Publication No. 09-051132-EF-1. Rockville, Maryland: Agency for Healthcare Research and Quality. May 2009.
Appendix 1: PubMed search terms and exclusion criteria
Appendix 2. Uspstf Hierarchy of Research Design and Quality Rating Criteria
