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U.S. Preventive Services Task Force Evidence Syntheses, formerly Systematic Evidence Reviews
U.S. Preventive Services Task Force Evidence Syntheses
public health

Chapter  11:  Hormone Replacement Therapy and Risk of Venous Thromboembolism

A2820

Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 2101 East Jefferson Street Rockville, MD 20852

http://www.ahrq.gov/

Contract No. 290-97-0018 Task Order No. 2 Technical Support of the U.S. Preventive Services Task Force

Prepared by: Oregon Health Sciences University Evidence-based Practice Center, Portland, Oregon Jill Miller, MD Benjamin K.S. Chan, MS Heidi Nelson, MD, MPH

August 2002

This report may be used, in whole or in part, as the basis for development of clinical practice gdelines and other quality enhancement tools, or a basis for reimbursement and coverage policies. AHRQ or U.S. Department of Health and Human Services endorsement of such derivative products may not be stated or implied.

AHRQ is the lead Federal agency charged with supporting research designed to improve the quality of health care, reduce its cost, address patient safety and medical errors, and broaden access to essential services. AHRQ sponsors and conducts research that provides evidence-based information on health care outcomes; quality; and cost, use, and access. The information helps health care decisionmakers -- patients and clinicians, health system leaders, and policymakers -- make more informed decisions and improve the quality of health care services.

Prepared for: Agency for Healthcare Research and Quality U.S. Department of Health and Human Services 2101 East Jefferson Street Rockville, MD 20852

http://www.ahrq.gov/

Contract No. 290-97-0018 Task Order No. 2 Technical Support of the U.S. Preventive Services Task Force

Prepared by: Oregon Health Sciences University Evidence-based Practice Center, Portland, Oregon Jill Miller, MD Benjamin K.S. Chan, MS Heidi Nelson, MD, MPH

August 2002

This report may be used, in whole or in part, as the basis for development of clinical practice gdelines and other quality enhancement tools, or a basis for reimbursement and coverage policies. AHRQ or U.S. Department of Health and Human Services endorsement of such derivative products may not be stated or implied.

AHRQ is the lead Federal agency charged with supporting research designed to improve the quality of health care, reduce its cost, address patient safety and medical errors, and broaden access to essential services. AHRQ sponsors and conducts research that provides evidence-based information on health care outcomes; quality; and cost, use, and access. The information helps health care decisionmakers -- patients and clinicians, health system leaders, and policymakers -- make more informed decisions and improve the quality of health care services.

Contents

Preface

Structured Abstract

Chapter 1. Introduction

Chapter 2. Methods

Chapter 3. Results

Chapter 4. Discussion

Acknowledgements

Appendix 1a. Search Strategy for Effects of Hormone Replacement Therapy on Coagulation

Appendix 1b. Search Strategy for Hormone Replacement Therapy Randomized Controlled Trials

Appendix 1c. Search Strategy for Selective Estrogen Receptor Modulators (SERMs)

Appendix 2. Hormone Replacement Therapy and Venous Thromboembolism Search Results

Appendix 3. Criteria for Grading the Internal Validity of Individual Studies

Appendix 4

References

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