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ContributorsPreface Seng-Lai Tan, Ph.D.Introduction David R. GretchChapter 1 HCV Genome and Life Cycle Stéphane Chevaliez and Jean-Michel Pawlotsky
Chapter 2 HCV 5′ and 3′UTR: When Translation Meets Replication Stephanie T. Shi and Michael M. C. Lai
Chapter 3 Assemble and Interact: Pleiotropic Functions of the HCV Core Protein Stephen J. Polyak, Kevin C. Klein, Ikuo Shoji, Tatsuo Miyamura, and Jaisri R. Lingappa
Chapter 4 HCV Glycoproteins: Assembly of a Functional E1–E2 Heterodimer Muriel Lavie, Anne Goffard, and Jean Dubuisson
Chapter 5 HCV NS2/3 Protease Sarah Welbourn and Arnim Pause
Chapter 6 HCV NS3-4A Serine Protease Chao Lin
Chapter 7 HCV Helicase: Structure, Function, and Inhibition David N. Frick
Chapter 8 HCV NS4B: From Obscurity to Central Stage Ella H. Sklan and Jeffrey S. Glenn
Chapter 9 HCV NS5A: A Multifunctional Regulator of Cellular Pathways and Virus Replication Yupeng He, Kirk A. Staschke, and Seng-Lai Tan
Chapter 10 Biochemical Activities of the HCV NS5B RNA-Dependent RNA Polymerase C. T. Ranjith-Kumar and C. Cheng Kao
Chapter 11 HCV Replicon Systems Keril J. Blight and Elizabeth A. Norgard
Chapter 12 Animal Models for HCV Study Linda B. Couto and Alexander A. Kolykhalov
Chapter 13 HCV Regulation of Host Defense D. Spencer Carney and Michael Gale Jr.
Chapter 14 Regulation of Adaptive Immunity by HCV Xiao-Song He
Chapter 15 Recombinant Vesicular Stomatitis Virus (VSV) and Other Strategies in HCV Vaccine Designs and Immunotherapy Ayaz M. Majid and Glen N. Barber
Chapter 16 Development of an Infectious HCV Cell Culture System Takaji Wakita and Takanobu Kato