-- Methods of Behavior Analysis in Neuroscience -- NCBI Bookshelf

Dedication
Series Preface
Preface
The Editor
Contributors
1 Transgenic Mouse Models of Alzheimer’s Disease: Behavioral Testing and Considerations Kathryn J. Bryan, Hyoung-gon Lee, George Perry, Mark A. Smith, and Gemma Casadesus
- INTRODUCTION
- BEHAVIORAL TESTS
- TRANSGENIC MOUSE MODELS OF ALZHEIMER’S DISEASE
- CONCERNS WITH TRANSGENIC MOUSE MODELS OF ALZHEIMER’S DISEASE
- REFERENCES
2 Cued and Contextual Fear Conditioning for Rodents Peter Curzon, Nathan R. Rustay, and Kaitlin E. Browman
- INTRODUCTION
- CONTEXTUAL/CUED FEAR CONDITIONING: OVERVIEW
- BRAIN AREAS INVOLVED
- BEFORE GETTING STARTED
- SAMPLE EXPERIMENTS
- DATA ANALYSIS
- SAMPLE DATA
- NONASSOCIATIVE FREEZING COMPLICATIONS
- FINAL NOTE
- ADDENDUM
- REFERENCES
3 Drug Discrimination Richard Young
- INTRODUCTION
- METHODS
- DRUGS AS STIMULI
- APPLICATIONS
- SUMMARY
- REFERENCES
4 Conditioned Place Preference Adam J. Prus, John R. James, and John A. Rosecrans
- INTRODUCTION
- RESEARCH DESIGN AND METHODOLOGICAL CONSIDERATIONS
- TRAINING AND TESTING
- DRUG STUDIES USING THE CONDITIONED PLACE PREFERENCE PARADIGM
- THE MESOLIMBIC DOPAMINE SYSTEM IS IMPORTANT FOR CONDITIONED PLACE PREFERENCE
- MECHANISMS MEDIATING CONDITIONED PLACE PREFERENCE FOR COMMON DRUGS OF ABUSE
- CONDITIONED PLACE PREFERENCE VERSUS SELF-ADMINISTRATION
- SUMMARY
- REFERENCES
5 Anxiety-Related Behaviors in Mice Kathleen R. Bailey and Jacqueline N. Crawley
- INTRODUCTION
- GENERAL METHODOLOGICAL CONSIDERATIONS
- PARADIGMS
- CONCLUSION
- REFERENCES
6 Behavioral Assessment of Antidepressant Activity in Rodents Vincent Castagné, Paul Moser, and Roger D. Porsolt
- INTRODUCTION
- METHODS
- TYPICAL APPLICATIONS
- ANALYSIS AND INTERPRETATION
- REPRESENTATIVE DATA
- COMPARISON WITH RELATED PROCEDURES
- REFERENCES
7 Assessing Attention in Rodents Philip J. Bushnell and Barbara J. Strupp
- INTRODUCTION
- MULTIPLE-CHOICE SERIAL REACTION TIME TASKS
- SIGNAL DETECTION TASKS WITH BLANK TRIALS
- ATTENTIONAL SET-SHIFTING
- SELECTING A TEST METHOD
- REFERENCES
- APPENDIX: NAMES AND ADDRESSES OF VENDORS DISCUSSED IN THE TEXT
8 The Behavioral Assessment of Sensorimotor Processes in the Mouse: Acoustic Startle, Sensory Gating, Locomotor Activity, Rotarod, and Beam Walking Peter Curzon, Min Zhang, Richard J. Radek, and Gerard B. Fox
- INTRODUCTION
- ACOUSTIC STARTLE
- SENSORY GATING
- MOTOR FUNCTION AND SPONTANEOUS EXPLORATION
- REFERENCES
- APPENDIX: EQUIPMENT SUPPLIERS
9 Intravenous Drug Self-Administration in Nonhuman Primates Leonard L. Howell and William E. Fantegrossi
- INTRODUCTION
- SURGICAL PROCEDURES
- SCHEDULES OF REINFORCEMENT
- RESEARCH APPLICATION AND DATA INTERPRETATION
- DISCUSSION
- REFERENCES
10 Contextually Induced Drug Seeking During Protracted Abstinence in Rats Jerry J. Buccafusco and Laura Shuster
- INTRODUCTION
- GENERAL METHODS
- METHODOLOGICAL DETAILS
- ACTUAL DATA
- DISCUSSION
- REFERENCES
11 Operant Analysis of Fronto-striatal Function in Rodents Máté D. Döbrössy, Simon Brooks, Rebecca Trueman, Peter J. Brasted, and Stephen B. Dunnett
- INTRODUCTION
- THE NEUROPATHOLOGICAL AND BEHAVIORAL PROFILE OF HD
- ANIMAL MODELS OF HD
- OPERANT CONDITIONING AND OPERANT CHAMBERS
- OPERANT ANALYSIS OF MOTOR RESPONDING: STRIATAL LESIONED AND HD TRANSGENIC ANIMALS
- OPERANT ANALYSIS OF COGNITIVE TASKS: STRIATAL LESIONED AND GENETICALLY MODIFIED HD MODELS
- OPERANT ANALYSIS OF STRIATAL LESIONS: DEFICITS IN MOTIVATIONAL STATE
- CONCLUSION
- REFERENCES
12 Working Memory Delayed Response Tasks in Monkeys Jesse S. Rodriguez and Merle G. Paule
- INTRODUCTION
- METHODS
- DATA ANALYSIS AND INTERPRETATION
- TYPICAL APPLICATIONS
- REPRESENTATIVE DATA
- LIMITATIONS AND CONCLUSIONS
- REFERENCES
13 Spatial Navigation (Water Maze) Tasks Alvin V. Terry Jr
- INTRODUCTION
- STANDARD PROCEDURES
- ALTERNATIVE PROCEDURES
- SUMMARY AND CONCLUSIONS
- REFERENCES
14 Water Maze Tasks in Mice: Special Reference to Alzheimer’s Transgenic Mice Dave Morgan
- INTRODUCTION
- METHODS
- REPRESENTATIVE DATA
- ANALYSIS AND INTERPRETATION
- REFERENCES
15 Behavioral Neuroscience of Zebrafish Edward D. Levin and Daniel T. Cerutti
- INTRODUCTION
- USE OF FISH MODELS IN BEHAVIORAL NEUROSCIENCE
- PROCEDURES AND PROCESSES
- CONCLUSIONS
- REFERENCES
16 Caenorhabditis elegans Model for Initial Screening and Mechanistic Evaluation of Potential New Drugs for Aging and Alzheimer’s Disease Yuan Luo, Yanjue Wu, Marishka Brown, and Christopher D. Link
- INTRODUCTION
- METHODS
- TYPICAL APPLICATIONS
- ANALYSIS AND INTERPRETATION
- REPRESENTATIVE DATA
- REFERENCES
17 The Revival of Scopolamine Reversal for the Assessment of Cognition-Enhancing Drugs Jerry J. Buccafusco
- INTRODUCTION
- METHODS
- SCOPOLAMINE REVERSAL
- DISCUSSION
- REFERENCES
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