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Final differentiation of a trunk neural crest cell committed to become either an adrenomedullary (chromaffin) cell or a sympathetic neuron. Glucocorticoids appear to act at two places in this pathway: first, they inhibit the actions of those factors that promote neuronal differentiation, and second, they induce those enzymes characteristic of the adrenomedullary cells. Those cells exposed sequentially to basic fibroblast growth factor (FGF2) and nerve growth factor (NGF) differentiate into the sympathetic neurons.