| Acromegaly | Serum GH/SmC | Nonstressed state: GH > 30 ng/ml SmC > 0.2 μg/ml diagnostic |
| Cushing's syndrome | Overnight 1 mg dexamethasone | Cortisol <5 μg/dl rules out diagnosis |
| Hyperthyroidism (nondiagnostic thyroxin) | Serum HS–TSH | <0.3 μU/ml consistent with diagnosis |
| Panhypopituitarism | Serum prolactin and TSH after TRH | Failure of both to double consistent with diagnosis |
| Serum cortisol after cosyntropin | Failure to exceed 18 μg/dl consistent with diagnosis |
| Serum deoxycortisol after metyrapone | <10 μg/dl consistent with diagnosis |
