Table of Contents
- Part I Introduction to the Cell
- Chapter 1 The Evolution of the Cell
- Introduction
- From Molecules to the First
Cell
- From Procaryotes to
Eucaryotes
- From Single Cells to Multicellular
Organisms
- References
- Chapter 2 Small Molecules, Energy, and Biosynthesis
- Introduction
- The Chemical Components of a Cell
- Biological Order and
Energy
- Food and the Derivation of Cellular
Energy
- Biosynthesis and the Creation of
Order
- The Coordination of Catabolism
and Biosynthesis
- References
- Chapter 3 Macromolecules: Structure, Shape, and Information
- Introduction
- Molecular Recognition
Processes
- Nucleic Acids
- Protein
Structure
- Proteins as
Catalysts
- References
- Chapter 4 How Cells Are Studied
- Introduction
- Looking at the Structure of Cells
in the Microscope
- Isolating Cells and Growing Them in
Culture
- Fractionation of Cells and Analysis
of Their Molecules
- Tracing and Assaying Molecules Inside Cells
- References
- Part II Molecular Genetics
- Chapter 5 Protein Function
- Introduction
- Making Machines Out of Proteins
- The Birth, Assembly, and Death of Proteins
- References
- Chapter 6 Basic Genetic Mechanisms
- Introduction
- RNA and Protein Synthesis
- DNA Repair
- DNA Replication
- Genetic
Recombination
- Viruses, Plasmids, and Transposable
Genetic Elements
- References
- Chapter 7 Recombinant DNA Technology
- Introduction
- The Fragmentation, Separation,
and Sequencing of DNA Molecules
- Nucleic Acid
Hybridization
- DNA Cloning
- DNA Engineering
- References
- Chapter 8 The Cell Nucleus
- Introduction
- Chromosomal DNA and Its
Packaging
- The Global Structure of Chromosomes
- Chromosome Replication
- RNA Synthesis and RNA Processing
- The Organization and Evolution of the Nuclear Genome
- References
- Chapter 9 Control of Gene Expression
- Introduction
- An Overview of Gene Control
- DNA-binding Motifs in Gene
Regulatory Proteins
- How Genetic Switches
Work
- Chromatin Structure and the Control
of Gene Expression
- The Molecular Genetic Mechanisms
That Create Specialized Cell Types
- Posttranscriptional Controls
- References
- Part III Internal Organization of the Cell
- Chapter 10 Membrane Structure
- Introduction
- The Lipid Bilayer
- Membrane Proteins
- References
- Chapter 11 Membrane Transport of Small Molecules and the Ionic Basis of Membrane Excitability
- Introduction
- Principles of Membrane
Transport
- Carrier Proteins and Active
Membrane Transport ,
- Ion Channels and Electrical Properties
of Membranes
- References
- Chapter 12 Intracellular Compartments and Protein Sorting
- Introduction
- The Compartmentalization of Higher Cells
- The Transport of Molecules into and
out of the Nucleus
- The Transport of Proteins into
Mitochondria and Chloroplasts
- Peroxisomes
- The Endoplasmic
Reticulum
- References
- Chapter 13 Vesicular Traffic in the Secretory and Endocytic Pathways
- Introduction
- Transport from the ER Through
the Golgi Apparatus
- Transport from the Trans Golgi Network to Lysosomes
- Transport from the Plasma Membrane
via Endosomes: Endocytosis
- Transport from the Trans Golgi Network
to the Cell Surface: Exocytosis
- The Molecular Mechanisms of
Vesicular Transport and the Maintenance
of Compartmental Diversity
- References
- Chapter 14 Energy Conversion: Mitochondria and Chloroplasts
- Introduction
- The
Mitochondrion
- The Respiratory Chain and ATP
Synthase
- Chloroplasts and
Photosynthesis
- The Evolution of Electron-Transport
Chains
- The Genomes of Mitochondria and Chloroplasts
- References
- Chapter 15 Cell Signaling
- Introduction
- General Principles of Cell
Signaling
- Signaling via G-Protein-linked
Cell-Surface Receptors
- Signaling via Enzyme-linked Cell-Surface Receptors
- Target-Cell Adaptation
- The Logic of Intracellular Signaling: Lessons from Computer-based "Neural Networks"
- References
- Chapter 16 The Cytoskeleton
- Introduction
- The Nature of the Cytoskeleton
- Intermediate
Filaments
- Microtubules
- Cilia and
Centrioles
- Actin Filaments
- Actin-binding
Proteins
- Muscle
- References
- Chapter 17 The Cell-Division Cycle
- Introduction
- The General Strategy of the Cell Cycle
- The Early Embryonic Cell Cycle
and the Role of MPF
- Yeasts and the Molecular Genetics
of Cell-Cycle Control
- Cell-Division Controls in Multicellular Animals
- References
- Chapter 18 The Mechanics of Cell Division
- Introduction
- An Overview of M
Phase
- Mitosis
- Cytokinesis
- References
- Part IV Cells in Their Social Context
- Chapter 19 Cell Junctions, Cell Adhesion, and the Extracellular Matrix
- Introduction
- Cell Junctions
- Cell-Cell
Adhesion
- The Extracellular Matrix of
Animals
- Extracellular Matrix Receptors on Animal Cells: The Integrins
- The Plant Cell Wall
- References
- Chapter 20 Germ Cells and Fertilization
- Introduction
- The Benefits of Sex
- Meiosis
- Eggs
- Sperm
- Fertilization
- References
- Chapter 21 Cellular Mechanisms of Development
- Introduction
- Morphogenetic Movements and
the Shaping of the Body Plan
- Cell Diversification in the Early
Animal Embryo ,
- Cell Memory, Cell Determination, and the Concept of Positional Values
- The Nematode Worm: Developmental
Control Genes and the Rules of Cell
Behavior
- Drosophila and the Molecular Genetics of Pattern Formation. I. Genesis of the Body Plan
- Drosophila
and the Molecular Genetics
of Pattern Formation. II. Homeotic Selector Genes and the Patterning of Body
Parts ,
- Plant
Development
- Neural
Development
- References
- Chapter 22 Differentiated Cells and the Maintenance of Tissues
- Introduction
- Maintenance of the Differentiated
State
- Tissues with Permanent
Cells
- Renewal by Simple
Duplication
- Renewal by Stem Cells:
Epidermis ,
- Renewal by Pluripotent Stem Cells:
Blood Cell Formation ,
- Genesis, Modulation, and Regeneration
of Skeletal Muscle
- Fibroblasts and Their Transformations:
The Connective-Tissue Cell Family
- Appendix
- References
- Chapter 23 The Immune System
- Introduction
- The Cellular Basis of Immunity
- The Functional Properties of
Antibodies
- The Fine Structure of Antibodies
- The Generation of Antibody Diversity
- T Cell Receptors and Subclasses
- MHC Molecules and Antigen Presentation
to T Cells
- Cytotoxic T Cells
- Helper T Cells and T Cell
Activation
- Selection of the T Cell Repertoire
- References
- Chapter 24 Cancer
- Introduction
- Cancer as a Microevolutionary
Process
- The Molecular Genetics of
Cancer
- References
Copyright © 1994 Bruce Alberts, Dennis Bray, Julian Lewis, Martin Raff, Keith Roberts, and James D. Watson. Published by Garland Publishing, a member of the Taylor & Francis Group. No part of the publication may be reproduced or used in any form or by any means known now or invented hereafter without the permission of the publisher.
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