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Hartwell D, Jones J, Baxter L, et al. Peginterferon Alfa and Ribavirin for Chronic Hepatitis C in Patients Eligible for Shortened Treatment, Re-Treatment or in HCV/HIV Co-Infection: A Systematic Review and Economic Evaluation. Southampton (UK): NIHR Evaluation, Trials and Studies Coordinating Centre (UK); 2011 Apr. (Health Technology Assessment, No. 15.17.)

Cover of Peginterferon Alfa and Ribavirin for Chronic Hepatitis C in Patients Eligible for Shortened Treatment, Re-Treatment or in HCV/HIV Co-Infection: A Systematic Review and Economic Evaluation

Peginterferon Alfa and Ribavirin for Chronic Hepatitis C in Patients Eligible for Shortened Treatment, Re-Treatment or in HCV/HIV Co-Infection: A Systematic Review and Economic Evaluation.

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List of abbreviations

ALT

alanine aminotransferase

BNF

British National Formulary

BSC

best supportive care

CC

compensated cirrhosis

CEA

cost-effectiveness analysis

CEAC

cost-effectiveness acceptability curve

CI

confidence interval

CrI

credible interval

CUA

cost–utility analysis

DC

decompensated cirrhosis

DSA

deterministic sensitivity analysis

EOT

end of treatment (virological response)

EQ-5D

European Quality of Life-5 Dimensions

EVR

early virological response

GGT

γ-glutamyltransferase

Gp

group

HAART

highly active antiretroviral therapy

HAI

histological activity index

Hb

haemoglobin

HCC

hepatocellular carcinoma

HCHS

hospital and community health services

HCV

hepatitis C virus

HIV

human immunodeficiency virus

HPA

Health Protection Agency

HRQoL

health-related quality of life

HTA

health technology assessment

ICER

incremental cost-effectiveness ratio

IDU

injecting drug user

ITT

intention to treat

IU

international unit

LT

liver transplantation

LVL

low viral load

MS

manufacturer's submission

MSM

men who have sex with men

NA

not available

NICE

National Institute for Health and Clinical Excellence

NR

not reported

pa

per annum

PCR

polymerase chain reaction

Post LT

post liver transplantation

PSA

probabilistic sensitivity analysis

PSS

Personal and Social Services

QALY

quality-adjusted life-year

QoL

quality of life

RCT

randomised controlled trial

RNA

ribonucleic acid

RR

relative risk/risk ratio

RVR

rapid virological response

SE

standard error

SG

standard gamble

SHTAC

Southampton Health Technology Assessments Centre

SPC

summary of product characteristics

SVR

sustained virological response

TA

Technology Appraisal

TAR

technology assessment report

TMA

transcription-mediated amplification

TTO

time trade-off

ULN

upper limit of normal

YLS

years of life saved

All abbreviations that have been used in this report are listed here unless the abbreviation is well known (e.g. NHS), or it has been used only once, or it is a non-standard abbreviation used only in figures/tables/appendices, in which case the abbreviation is defined in the figure legend or in the notes at the end of the table.

© 2011, Crown Copyright.

Included under terms of UK Non-commercial Government License.

Bookshelf ID: NBK99710
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