From: Chromosomal Sex Determination in Mammals
Copyright © 2000, Sinauer
Associates.
Figure 17.9
Phenotypic sex reversal in humans having two copies of the DAX1 locus. DAX1 (on the X chromosome) plus SRY (on the Y chromosome) produces testes. DAX1 without SRY (since the other DAX1 locus is on the inactive X chromosome) produces ovaries. Two active copies of DAX1 (on the active X chromosome) plus SRY (on the Y chromosome) lead to a poorly formed gonad. Since the gonad makes neither AMH nor testosterone, the phenotype is female. (After Genetics Review Group 1995.)
- Figure 17.9, [Phenotypic sex reversal in humans...]. - Developmental BiologyFigure 17.9, [Phenotypic sex reversal in humans...]. - Developmental BiologyBookself
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